Tagged / research

NIHR Clinical Research Network Portfolio

The National Institute for Health Research (NIHR) is one of the largest funders of clinical research in Europe and have a number of funding streams that you can apply for in order to conduct health-related research. The NIHR then has a number of Clinical Research Networks or ‘CRNs’ that are spread out to each region of England. The local CRN is Wessex, based in Hedge End, Southampton.

The ‘Portfolio’

At the heart of CRN activities is the NIHR CRN Portfolio of studies. This consists of high-quality clinical research studies that are eligible for consideration for support from the CRN in England. Adoption onto the portfolio has a number of benefits for researchers, such as help in identifying potential research sites, access to patients and the public to carry out ‘PPI‘ and advice on recruitment strategy at any point during the study. The CRN offers support to researchers via their Study Support Service and likewise via each portfolio manager and their team. You can see a breakdown of each portfolio here on the Wessex CRN page.

The Portfolio and the NHS

Portfolio adoption is usually vital to participating NHS Trusts when considering the research studies they wish to undertake, as they are reimbursed for the resource given to conduct the study (e.g. research nurse support, data manager time). As a result, it is strongly advised that external funding is considered for BU clinical research projects – the amount of funding doesn’t have to be substantial.

Each CRN is given a budget for the financial year by the NIHR, which is then distributed to sites based on their recruitment figures.

Requirements

In order to be eligible for portfolio adoption, there are three criteria a study must meet:

  • The study must be ‘research’ (this is stipulated, as often what’s classed as research outside the NHS setting, is sometimes a service evaluation, quality improvement etc. within the NHS – see this table);
  • Have appropriate ethical approval; and Health Research Authority (HRA) Approval where required;
  • Have full research funding – this has to have been awarded via open competition and by the NIHR, other areas of central Government, or an NIHR non-commercial partner (for which there is a list). If the study has received support from multiple funders, then it will be still considered automatically eligible, if one of the funding streams is the NIHR, an area of central Government or a non-commercial partner.

You can read more about study eligibility here, including research funded by overseas partners.

The Portfolio and BU

The source of research funding is the principal determinant of eligibility for NIHR CRN support and so it is encouraged that researchers seek external funding where possible and appropriate, from the NIHR, another area of central Government or one of their non-commercial partners. The amount of funding doesn’t need to substantial in order to be eligible.

For any queries to do with the portfolio or for guidance regarding implementing your research in a healthcare setting, take a look at the Clinical Governance blog. You can also get in touch with BU’s Research Ethics team with any queries.

Workshop available – Ethical Thinking and Decision-making in Practice

Are you new or relatively new to research? Are you interested in attending a workshop that will allow you to improve your understanding and confidence in the application of ethical considerations to your research activity? Then take advantage of the following opportunity!

Dr Helen Kara will be delivering a one-day workshop on Monday 17th June, 09:30 – 16:30 on Talbot Campus, entitled Ethical Thinking and Decision-making in Practice.

The aims & objectives of this sessions are to:

  • To increase their awareness of the need for ethics compliance in research and, by the end of the workshop, be aware of their responsibilities and when to seek further assistance
  • To develop their skills in the following key areas, within the context of ethical research:
    a. Planning and design
    b. Gathering data and data analysis
    c. Reporting, including presentation and dissemination
    d. Consideration of ethical dilemmas, based on real-world examples and participants’ experience

If you want to book onto this workshop and take advantage of this great opportunity, then please see the following page for instructions.
If you are a PGR, please email Organisation Development to book your place.

Setting up NHS / HSC research in the UK– changes from TODAY

The new ‘UK Local Information Pack‘  has been introduced today, 5th June to support the set-up of NHS / HSC research in the UK.

The ‘UK Local Information Pack’ is the set of documents that NHS / HSC organisations use to formally start preparing to deliver the study. You can find more information here, including what comprises the pack. All researchers wishing to set-up their study at an NHS/HSC site from today, 5th June, need to be aware of this change.

The Organisation Information Document

Researchers and research teams may be aware of a document called the ‘Statement of Activities’ – this is essentially a document that allows the sponsor to make clear to the research site, what activities will be undertaken locally. The document can also act as the agreement between the sponsor and site.

From today the Statement of Activities has been replaced by a document called the ‘Organisation Information Document‘. For non-commercially sponsored studies, that are not clinical trials or clinical investigations, the ‘Organisation Information Document’ should be used as the agreement between sponsor and participating NHS / HSC organisation.

A new delegation log template

Another feature of the new UK Local Information Pack is the inclusion of a delegation log template, which is intended to be used at participating NHS / HSC organisations. This will allow NHS/HSC organisations to locally record who will be working on the study and who is authorised to undertake study tasks. The delegation log can be found here and should be used for studies submitted for approvals from today.

Schedule of Events or Schedule and Events Cost Attribution Tool (SoECAT)

For non-commercially sponsored studies studies an IRAS Schedule of Events or a SoECAT will be a part of the IRAS Form submission and is used in the UK Local Information Pack as a way of providing clarity to participating NHS / HSC organisations on the cost attributions associated with a study.

Further help and guidance

Guidance on the use of the new UK Local Information Pack has now been published in the Site Specific page of IRAS Help to help applicants get ready for the change.

If you are making an IRAS Form submission or planning to set up research in an NHS / HSC organisation from today, 5th June 2019 please read the transition guidance so that you prepare the correct materials.

If you have any queries regarding any of the information provided above, or would like some guidance with regard to implementing your research in a healthcare setting – please get in touch with BU’s Research Ethics team.

You can also take a look at the Clinical Governance blog for documents, links and training opportunities.

Knowledge of research methods is not enough, having a ‘story’ is more important.

BU PGR Adedoyin Festus Fatai was one of three PhD students accepted to present at a 3-days intensive workshop on “Tourism: Economics and Management. Tourists as Consumers, Visitors and Travelers” in honour of Lionello F. Punzo which held at the Department of Economics, University of Siena, Siena, Italy (Italia), between 30 May – 1 June 2019.

It was an invaluable experience to serve as a discussant alongside other researchers in the field and to receive feedback on one of the empirical chapters from my PhD research. Additionally, there were comments from well-experienced journal editors with opportunities for collaboration.

An important lesson from the 15 papers discussed is that knowledge of research methods is not enough! instead, having a ‘story’ is more important. A good story will always sell as long as it identifies a clear gap to fill; is significant and has a strong motivation for it to be published in a journal with high impact factor.

 

Adedoyin

Festus

Impact Case Study Writing Retreat

Thursday 6th June 09:30 – 16:30

A whole day REF impact case study writing retreat, consisting of a two hour presentation on case study writing with the rest of the day spent writing. The trainer will be on hand the whole day to provide 1:1 support and guidance. Attendees are required to have an impact case study to write and work on; own laptop is required for the session.

The writing retreat will provide guidance on:

  • How to write and excellent impact case study
  • How to frame the writing
  • What a successful case study looks like
  • Other hints and tips towards successful impact case study writing
  • Guiding individual attendees during the personal writing elements

If you can’t make the retreat on 6th June, there is another scheduled for 4th July.

See here for more details and to book.

NIHR Research Participant Experience Survey 2018/19 – final report

You may have seen the blog post back in April regarding the results from a recent patient research experience survey, conducted by National Institute for Health Research (NIHR) Clinical Research Network (CRN) Wessex.

The survey results showed that across the 10 NHS organisations in Wessex, from the 400 responses received, 96% of participants had a good experience of taking part in research. It also showed that 98% of research participants surveyed had all the information that they needed in relation to the study.

The NIHR have released a recent report that shares the results of the Research Participant Experience Survey 2018-19, which was also conducted across the other 14 Clinical Research Network areas in England. You can take a look at the report here.

Writing About Methods

This workshop, delivered by publishing expert Patrick Brindle, aims to give participants a range of practical approaches to writing about methods in your research bids.

He uses a range of exercises. The workshop covers around 20 writing strategies, and provides more clarity and power to the often-difficult challenge of writing about methods. The course also looks at common mistakes and how to avoid them when writing about methods. The focus throughout is on building confidence and increasing your repertoire of writing strategies and skills.

Tuesday June 4th 09:30 – 16:30

See here for more information and to book on.

Please contact Alexandra Pekalski if you have any queries.

UK Data Service Events: May – July

The UK Data Service provides researchers with trusted, flexible support, training and access to the UK’s largest collection of social, economic and population data. They also organise a wide range of free events. Click on the links below for more information on, and to book for, the following events:

Workshops

Understanding census microdata for research purposes using the Scotland data collection

30 May 2019, 10.00 – 13.00

Administrative Data Research Centre – Scotland

Are you interested in learning more about census microdata and how they can be used in research? Have you considered using census data but are not sure what is available? This free workshop will introduce you to the UK Data Service census microdata collection and the Scottish Longitudinal Study. Although the census microdata collection covers the UK as a whole, this workshop will have a special emphasis on the collection for Scotland.

Webinars

Webinar: Key issues in reusing data

23 May 2019, Online, 15.00 – 16.00 BST

Participants will hear about the key issues in secondary analysis as a method. The introductory session will briefly cover the pros and cons of reusing data and the importance of learning about the origins of your data. Quantitative and qualitative secondary analysis will be discussed with examples and issues of context, sampling and ethics will be raised.

Webinar: Guided walk through ReShare

6 June 2019, Online, 15.00 – 16.00 BST

Are you an ESRC grant holder, whose grant has ended and is required to submit your research data into the ReShare repository? Are you a researcher interested in depositing data into ReShare to make them available for reuse, or as evidence for a published paper? Are you just curious to explore how publishing in ReShare happens in practice? Join our interactive online webinar, where we will ‘ walk’ you through the process of submitting a data collection into the ReShare repository. We will then answer any questions you may have about ReShare and depositing your data with us.

Designing user-centred engagement strategies for online-first surveys – part of the ONS Social Survey Transformation Project

27 June 2019, Online, 15.00 – 16.00 BST

The Office for National Statistics (ONS) is transforming the way its surveys collect data. It is introducing an online mode and designing for a web-first approach to mixed-mode collection, which brings challenges and opportunities. This webinar will be presented by Natalia Stutter, a Senior Research Officer at ONS. Natalia will describe how ONS is transforming the respondent communication strategy and user journey to help tackle barriers to opening letters and achieving a good response rate in online-first and mixed mode social surveys.

Developing a user-centred, web-first approach to collecting socio-demographic and household data – part of the ONS Labour Force Survey Transformation Project

1 July 2019, Online, 15.00 – 16.00 BST

The Office for National Statistics (ONS) is transforming the way its surveys collect data. It is introducing an online mode, and designing for a web-first approach to mixed-mode collection, which brings challenges and opportunities. This webinar will be presented by Emma Dickinson, a Senior Research Officer at ONS. Emma will describe how ONS is developing a respondent-centric approach to moving survey data collection online, with a specific focus on collecting household and sociodemographic information.

User Conferences

Family Finance Surveys User Conference 2019

19 June 2019, 9.30 – 16.30
Lift, Islington, London

Organised by the UK Data Service in collaboration with the Department for Work and Pensions and the Office for National Statistics. The programme contains a mixture of papers from data producers and researchers, including presentations based on analysis of the UK family finance surveys. The conference will allow users to hear updates from the data producers on the main surveys, including the Family Resources Survey, Living Costs and Food Survey, and the Wealth and Assets Survey.

Health Studies User Conference 2019

10 July 2019
University College London

The annual Health Studies User Conference, organised by the UK Data Service in collaboration with UCL and NatCen Social Research, is a full-day conference and is free to attend. The conference will allow users to hear updates from the data producers on key UK cross-sectional health surveys and key UK longitudinal studies with health-related content.

Other events

Open data dive: Plastic use reduction

6 July 2019

Federation House, Manchester

The UK Data Service and methods@manchester are running an Open Data Dive on plastic use reduction. The data dive will bring together coders, data enthusiasts, graphic designers, project managers and pizza lovers to analyse and visualise open social and economic data about plastic use reduction.

The Challenge: Local to global: The data in plastic, from single use carrier bags to international emissions from plastic manufacture – data strategies for plastic reuse reduction.

We are delighted to be welcoming some special guests including Duncan Millard, Chief Statistician, and Head of the IEA Energy Data Centre to speak about the increasing use of oil for non-energy uses and the wealth of international data relating to plastic manufacture, usage and waste.

Setting up NHS / HSC research in the UK– upcoming changes

The UK Local Information Pack

A ‘UK Local Information Pack‘ will be introduced on the 5 June 2019 to support the set-up of NHS / HSC research in the UK.

The ‘UK Local Information Pack’ is the set of documents that NHS / HSC organisations use to formally start preparing to deliver the study. You can find more information here, including what comprises the pack. All researchers wishing to set-up their study at an NHS/HSC site from 5 June, will need to be aware of this change.

The Organisation Information Document

Researchers and research teams may be aware of a document called the ‘Statement of Activities’ – this is essentially a document that allows the sponsor to make clear to the research site, what activities will be undertaken locally. The document can also act as the agreement between the sponsor and site. Researchers setting up their study before 5 June should continue to use this document.

From 5 June the Statement of Activities will be replaced by a document called the ‘Organisation Information Document‘. For non-commercially sponsored studies, that are not clinical trials or clinical investigations, the ‘Organisation Information Document’ should be used as the agreement between sponsor and participating NHS / HSC organisation.

A new delegation log template

Another feature of the UK Local Information Pack is the inclusion of a delegation log template, which is intended to be used at participating NHS / HSC organisations. This will allow NHS/HSC organisations to locally record who will be working on the study and who is authorised to undertake study tasks.

Schedule of Events or Schedule and Events Cost Attribution Tool (SoECAT)

For non-commercially sponsored studies studies an IRAS Schedule of Events or a SoECAT will be a part of the IRAS Form submission and is used in the UK Local Information Pack as a way of providing clarity to participating NHS / HSC organisations on the cost attributions associated with a study.

Further help and guidance

Guidance on the use of the UK Local Information Pack has now been published in the Site Specific page of IRAS Help to help applicants get ready for the change.

If you are making an IRAS Form submission or planning to set up research in an NHS / HSC organisation from 5 June 2019 please read the transition guidance so that you prepare the correct materials.

If you have any queries regarding any of the information provided above, or would like some guidance with regard to implementing your research in a healthcare setting – please get in touch with BU’s Research Ethics team.

You can also take a look at the Clinical Governance blog for documents, links and training opportunities.

Article published in Physiological Reports

 

The article titled “The effects of 8 weeks of inspiratory muscle training on the balance of healthy older adults: a randomized, double-blind, placebo-controlled study” has been published by Physiological Reports.

 

It is the first research to describe the effects of inspiratory muscle training (i.e. breathing exercises that improve the strength of inspiratory muscles) on static and dynamic balance (measured with the clinical tool mini-BEST) and functional mobility (such as Timed Up and Go and 5 sit to stand tasks) with community dwellers older adults (aged 65+).

The research is part of Francesco Ferraro PhD journey. Journey guided with the supervision of Professor Alison McConnell, Dr James Gavin and Tom Wainwright

The article is now fully available as open access here

https://doi.org/10.14814/phy2.14076

Abstract

To examine the effects of 8‐week unsupervised, home‐based inspiratory muscle training (IMT) on the balance and physical performance of healthy older adults. Fifty‐nine participants (74 ± 6 years) were assigned randomly in a double‐blinded fashion to either IMT or sham‐IMT, using a pressure threshold loading device. The IMT group performed 30‐breath twice daily at ~50% of maximal inspiratory pressure (MIP). The sham‐IMT group performed 60‐breaths once daily at ~15% MIP; training was home‐based and unsupervised, with adherence self‐reported through training diaries. Respiratory outcomes were assessed pre‐ and postintervention, including forced vital capacity, forced expiratory volume, peak inspiratory flow rate (PIFR), MIP, and inspiratory peak power. Balance and physical performance outcomes were measured using the shortened version of the Balance Evaluation System test (mini‐BEST), Biodex® postural stability test, timed up and go, five sit‐to‐stand, isometric “sit‐up” and Biering–Sørensen tests. Between‐group effects were examined using two‐way repeated measures ANOVA, with Bonferroni correction. After 8‐week, the IMT group demonstrated greater improvements (P ≤ 0.05) in: PIFR (IMT = 0.9 ± 0.3 L sec−1; sham‐IMT = 0.3 L sec−1); mini‐BEST (IMT = 3.7 ± 1.3; sham‐IMT = 0.5 ± 0.9) and Biering–Sørensen (IMT = 62.9 ± 6.4 sec; sham‐IMT = 24.3 ± 1.4 sec) tests. The authors concluded that twice daily unsupervised, home‐based IMT is feasible and enhances inspiratory muscle function and balance for community‐dwelling older adults.