Posts By / inessel

BU research into breast milk quality-Participants needed

 

We are looking for breast feeding mums to donate 5 mL of breast milk for a research study conducted at BU.

When mother’s own milk is not sufficient or appropriate, preterm babies can be fed with donor milk from a human milk bank. However, the processes used in milk banking might increase the risk of fat degradation in the milk. Currently, nothing is known about fat degradation products in donor milk. With this study, we aim to quantify fat degradation products in donor milk, and we are currently looking for some term breast milk to compare our results to.

If you are breastfeeding and would like to take part in the study, please get in touch!

Please feel free to share the information with any breastfeeding mum you know!

If you want to know more about milk banking in the UK, read my earlier blog post here.

Many thanks, Isabell

inessel@bournemouth.ac.uk

01202965009

BU research into breast milk quality-Participants needed

 

We are looking for breast feeding mums to donate 5 mL of breast milk for a research study conducted at BU.

When mother’s own milk is not sufficient or appropriate, preterm babies can be fed with donor milk from a human milk bank. However, the processes used in milk banking might increase the risk of fat degradation in the milk. Currently, nothing is known about fat degradation products in donor milk. With this study, we aim to quantify fat degradation products in donor milk, and we are currently looking for some term breast milk to compare our results to.

If you are breastfeeding and would like to take part in the study, please get in touch!

Please feel free to share the information with any breastfeeding mum you know!

If you want to know more about milk banking in the UK, read my earlier blog post here.

Many thanks, Isabell

inessel@bournemouth.ac.uk

01202965009

BU’s PGR student Isabell Nessel has been awarded New Investigator Award and will be presenting at the 13thCongress of the International Society for the Study of Fatty Acids and Lipids (ISSFAL)

The 13th Congress of the International Society for the Study of Fatty Acids and Lipids (ISSFAL) http://www.issfal.org/ will be held in Las Vegas, USA in May 2018. BU will be highly represented at this biennial congress, which is the biggest and most prestigious congress in the field of fatty acid and lipid research. Isabell Nessel, a third year PhD student in the Faculty of Health and Social Sciences, will present her PhD work at this congress. She is supervised by Dr Simon Dyall and Prof Minesh Khashu.

Her research aims to investigate ways to increase the intake of long-chain polyunsaturated fatty acids in the perinatal period and to address whether this intake is associated with any adverse effects, due to the susceptibility of the fatty acids to oxygen-related damage. Isabell secures a prestigious oral presentation, and is also presenting two posters at this international congress, which expects around 800 delegates!

Isabell was awarded a full Santander Mobility Award to cover the travel costs to Las Vegas. Furthermore, Isabell won a New Investigator Award, which is granted by ISSFAL in conjunction with the Congress to recognise and encourage excellent abstract submissions.

The Congress will be an excellent opportunity for her to present her PhD work, and to learn about the latest research and the newest methods.

Isabell would like to express her gratitude to Santander, ISSFAL, and Bournemouth University for making this trip possible, and to her supervisors Dr Simon Dyall and Prof Minesh Khashu for their support with the applications and abstracts!

 

Look out for her blog post after the conference.

If you would like to know more about her research in the meantime, e-mail her at inessel@bournemouth.ac.uk

BU’s PGR Isabell Nessel at the 4th International Congress of the European Milk Bank Association

 

The European Milk Bank Association (EMBA) (www.europeanmilkbanking.com) held its 4th International Congress in Glasgow in early October. After a civic reception from Glasgow’s Mayor, at Glasgow’s magnificent City Chambers, the conference started with a warm welcome from Scotland’s Minister for Public Health and Sport.

Debbie Barnett, Donor Milk Bank Coordinator of the Scottish Greater Glasgow and Clyde Donor Milk Bank, and Jean-Charles Picaud, President of EMBA, welcoming the conference attendants.

Although it was a European conference, attendants from 35 countries from all over the world exchanged their research results, knowledge, and experience about human milk banking, with the aim to support the health of (preterm) babies. One important topic of the conference was the research into better thermal treatment of donor human milk. (http://embacongress.it/documenti/Program20170920.pdf)

I presented the results of our national milk bank survey, which we conducted earlier this year. The study was the first national audit of human milk banking practices in the U.K. with the aim to protecting and preserving omega-3 and omega-6 long chain polyunsaturated fatty acids in donor human milk. The survey identified large variations in all practices of human milk banking, including, donor selection, transportation, and storage and handling of donor milk, and nutritional information provided for donors.

This conference was a perfect opportunity for me, to talk to the respondents of the audit, to present our results, and to network with potential collaborators to facilitate further research into donor human milk in the U.K.

Many thanks to EMBA for the invitation to present my research, to all the participants of the survey, and to BU for the funding to attend this conference.

If you would like to learn more about human milk banking in the U.K. please visit the UK Association for Milk Banking website http://www.ukamb.org/

If you would like to learn more about our research, please feel free to contact me at inessel@bournemouth.ac.uk

Isabell

BU’s PGR Isabell Nessel at the Department of Life Sciences, University of Roehampton

 I had the pleasure of spending the last three weeks in the Department of Life Sciences (University of Roehampton), working with Dr Giulia Corona and Dr Volker Behrends. We successfully validated an ultra-high performance liquid chromatography coupled with triple quadrupole mass spectrometry (UPLC-MS/MS) method to analyse lipid peroxidation products (breakdown products of fats) in human urine samples.

Our ultimate goal is to identify the time-course of oxidative stress and subsequent breakdown of lipids in neonates, by analysing urinary lipid peroxides, to facilitate evidence-based approaches to antioxidant support in preterm neonates. My supervisors Dr Simon Dyall and Prof Minesh Khashu and I are currently developing a pilot study in cooperation with Poole Hospital NHS Foundation Trust to test the feasibility of measuring these products in urine samples from preterm neonates. However, before moving on to preterm samples, the method had to be tested and validated, using adult urine samples.

The project was made possible by an HSS Seed Corn fund obtained by Dr Simon Dyall, the PGR fund of Isabell Nessel, the collaboration with Dr Giulia Corona and Dr Volker Behrends at the Department of Life Sciences (University of Roehampton) and collaboration with Dr Thierry Durand and his group from the Institute des Biomolecules Max Mousseroux, (Montpellier, France) who generously provided the standards used in this analysis. I am grateful that I had this opportunity to further develop my research skills and to learn a new state-of-the-art technique and would like to thank all involved for making this possible!

If you would like to learn more about our research please feel free to contact me at inessel@bournemouth.ac.uk

Isabell

Fundraising for the Hearts Milk Bank at BU

On the 17th of November, The World Prematurity Day, there was a fundraising cake sale for the Hearts Milk Bank.

cake-saleThe amount raised will help to either

– feed 14 babies for a day

–  or feed 3 babies for 5 days, the average time they need donor milk

– or buy enough containers for 55 mums to start donating milk

– or buy almost 3  transportation bags.

The Hearts Milk Bank is therefore 1 step closer to provide donor milk for babies born too soon or too sick!

 

I would like to thank anyone who has made this cake sale possible, the bakers and the buyers, the great people who donated money, SUBU, and the people helping me on the day. You are awesome!

Gillian Weaver, co-founder of the bank contacted me to say “We are so grateful to you Isabell and to everyone who supported your cake sale on World Prematurity Day. You raised a fantastic amount and we will put it to very good use helping to ensure that all premature and sick babies get access to safe and assured supplies of donor milk irrespective of where they are born in the UK. We know that this not only helps to prevent tiny babies from life threatening illnesses but also supports their mothers whilst they build up their own breastmilk supply. The Hearts Milk Bank (the bank with a difference) will also be a biobank of breastmilk samples for much needed research into breast cancer so your support for us is doubly valuable!”

ukamb_logo2If you would like to learn more about donor milk visit the website of the UK Association for Milk Banking.

gkjo6pcssbgobqmecfa6If you would like to learn more about the Hearts Milk Bank or would like to donate, please click here: https://www.indiegogo.com/projects/hearts-milk-bank-saving-tiny-babies-helping-mums-cancer

 

I learned about donor milk as part of my PhD thesis at BU, focusing on the effects of omega-3 and omega-6 fatty acids in the perinatal period. If you are interested in our research please contact me at inessel@bournemouth.ac.uk

Many thanks, Isabell

World Prematurity Day – 17th November – Cake Sale

Would you donate a cake/cupcakes?

 

picture3Date:   17th November

Time:   11.30-13.30

  Venue: BoHo Lounge, Ground floor, Bournemouth House

Cake drop off on the morning of the 17th in R304 or B112a

 

picture1Preterm born babies are at high risk to develop a wide range of complications.

Some of these complications can be prevented by feeding babies with human breast milk.

Therefore, the WHO recommends human donor milk as best alternative if mother’s own milk is not available!

 

picture2The HEARTS MILK BANK is currently crowd funding to buy the needed equipment to start providing donor milk for babies born too soon or too sick, to improve their chance of survival and health!

All money from the cake sale will be directly donated to the Hearts Milk Bank!

 

 

If you want to donate a cake or receive  more information please contact

Isabell Nessel inessel@bournemouth.ac.uk

 

 

BU’s PhD Isabell Nessel at the Human Milk Bank in Southampton, Princess Anne Hospital

human-milk-bank-southamptonMost of you have probably heard/read about human milk banking by now from me or my previous posts, if not read here more about it. This week, I had the opportunity to meet Anita Holloway-Moger, the Human Milk Bank Nursery Nurse at the Princess Anne Hospital Human Milk Bank in Southampton.

It was a great opportunity to finally visit and see a milk bank and speak to the person responsible to gain more practical insight into human milk banking in the UK, instead of only reading about it for my research.

human-donor-milk
Human donor milk comes from mothers who have had several blood tests and is collected from the mothers’ homes by the milk bank staff and/or the blood bikes. The frozen milk then gets processed in the milk bank, which means it is tested for microbiological contamination and pasteurised (heat treated) to make it save for the premature or sick babies to receive. This has been shown to increase their chance of survival and help their development.
Thank you Anita for taking all the time to answer my questions and for showing me around, as well as Bournemouth University for the funding which made my trip possible!

 

UKAMBIf you would like to find out more about human milk banking in the UK or want to become a human milk donor visit the UK Association for Milk Banking website at http://www.ukamb.org/.

 

If you would like to learn more about our research, please feel free to contact me at inessel@bournemouth.ac.uk

Isabell

BU’s PhD student Isabell Nessel attending the UK Association for Milk Banking annual training day in London, 8th of June

UKAMB Training Day2

The UK Association for Milk Banking (UKAMB) recently held their annual training day in London (Picture: Isabell and UKAMB’s Trustee Chair Ann McCrea). Mostly, milk bank staff were present; however, the training day is also open to anyone interested in human milk banking. Therefore, milk donors, medical researchers, midwives, neonatal nurses and clinicians were also in attendance. The presentations included current topics such as the Zika virus and the implications for milk banking, new guidance on decontamination of breast milk pumps and an update of ongoing research at donor milk banks.

As part of this, I presented my proposed donor milk bank survey, which is part of my PhD at BU. I received a great deal of helpful feedback and support from UKAMB and the audience. It was a great opportunity to get more insights into human milk banking and ongoing research in the UK and to network with potenital participants of the survey and possible future collaborators. Thanks to Bournemouth University for the funding, which made my attendance possible!

A big thank you also goes to Gillian Weaver and UKAMB for the invitation,UKAMB and this great, informative day! If you would like to find out more about human milk banking in the UK or want to become a milk donor visit UKAMB’s website at http://www.ukamb.org/.

If you would like to learn more about our research, please feel free to contact me at inessel@bournemouth.ac.uk

Isabell

Human Milk Banking in the UK

UKAMBBreast feeding is the gold standard for feeding babies. This might not be surprising for most of you, although the rates of exclusive breast feeding in the UK are low. But have you ever heard of human milk banking? The UK Association for Milk Banking (UKAMB) does an incredible job in providing safe and screened donor breast milk all over the country through 16 donor milk banks, mostly to preterm babies whose mothers cannot provide sufficient breast milk. Feeding human donor milk instead of formula milk is for example associated with a lower risk for the severe gut infection necrotising enterocolitis.

Breast milk and donor milk also contain omega-3 and omega-6 polyunsaturated fatty acids, which are essential for brain and visual development in early infancy. However, research based at BU has identified that the current intake levels of preterm infants are too low to match the in utero accretion rates. Therefore, the aim of my PhD project at BU is to investigate approaches to increase the intake of omega-3 and omega-6 polyunsaturated fatty acids in preterm babies to improve their outcomes. One aspect I will be looking at is the intake from donor milk. Therefore, I was invited by the UK Association for Milk Banking to give a short presentation about my research at their annual training day in June.

I am looking forward to meeting donor milk bank staff and other researchers in the field of human milk banking at this day. I will post more details after the event. If you have any questions in the meantime, please feel free to contact me at inessel@bournemouth.ac.uk

If you would like to find out more about human milk banking in the UK or want to become a milk donor visit UKAMB’s website at http://www.ukamb.org/.

Isabell