BU Research Blog

Colleen Deane has recently joined the School of Health and Social Care to commence a BU matched funded PhD studentship investigating novel mechanisms regulating muscle mass in the elderly. Colleen has just successfully completed her Masters (with distinction) in Physical Activity, Nutrition and Health Promotion, where she investigated the effects of specific hormones (Testosterone) and polyphenols (Resveratrol) on artificially aged skeletal muscle cells, extracted from rodent mice. This PhD aims to enhance current understanding of the mechanisms regulating age-related loss of skeletal muscle mass (termed ‘sarcopenia’) and the associated reductions in mobility, general health and quality of life. Whilst exercise and nutritional interventions improve muscle size and function in young individuals, this response is attenuated in elderly muscle. Thus, using a combination of physiological and metabolic/molecular techniques these studies will investigate novel mechanisms underlying the blunted response of ageing muscle to exercise and nutritional growth stimuli. For further information contact Colleen on cdeane@bournemouth.ac.uk.