Tagged / longitudinal studies

Pregnancy & COVID-19 in UK: New study published

NHS, Women's Academic Network, writing

This morning the editor of the Frontiers in Psychiatry emailed us that the paper reporting the findings of the baseline data of a large-scale epidemiological study into pregnancy during COVID-19 in the UK has been published [1].  The interdisciplinary research team includes researchers from University Hospitals Dorset NHS Foundation Trust (Dr. Latha Vinayakarao & Prof. Minesh Khashu) and Bournemouth University (Prof. Edwin van Teijlingen). 

This longitudinal study explores how the SARS-CoV-2 [COVID-19] pandemic affected the mental health of pregnant people in the UK.  In mid-to-late 2020, we recruited 3666 individuals in the UK for the EPPOCH pregnancy cohort (Maternal mental health during the COVID-19 pandemic: Effect of the Pandemic on Pregnancy Outcomes and Childhood Health). Participants were assessed for depression, anxiety, anger and pregnancy-related anxiety using validated scales. Additionally, physical activity, social support, individualized support and personal coping ability of the respondents were assessed as potential resilience factors.

Participants reported high levels of depression (57.05%), anxiety (58.04%) and anger (58.05%). Higher levels of social and individualized support and personal coping ability were associated with lower mental health challenges. Additionally, pregnant individuals in the UK experienced higher depression during the pandemic than that reported in Canada. Finally, qualitative analysis revealed that restrictions for partners and support persons during medical appointments as well as poor public health communication led to increased mental health adversities and hindered ability to make medical decisions.

The study highlights the increased mental health challenges among pregnant individuals in the UK during pandemic. These results highlight the need for reassessing the mental health support measures available to pregnant people in the UK, both during times of crisis and in general.

Reference:

  1. Datye, S., Smiljanic, M., Shetti, R.H., MacRae-Miller, A., van Teijlingen, E., Vinayakarao, L., Peters, E.M.J., Lebel, C.A., Tomfohr-Madsen, L., Giesbrecht, G., Khashu, M., Conrad, M.L. (2024) Prenatal maternal mental health and resilience in the United Kingdom during the SARS-CoV-2 Pandemic: A cross-national comparison, Frontiers in Psychiatry, 15 https://doi.org/10.3389/fpsyt.2024.1411761

First EPPOCH study paper accepted for publication

open access, Publishing, writing

This afternoon the editorial office of Frontiers in Psychiatry informed us that our manuscript “Prenatal maternal mental health and resilience in the United Kingdom during the SARS-CoV-2 Pandemic: A cross-national comparison” [1] has been accepted for publication in Frontiers in Psychiatry, section Perinatal Psychiatry.   An interdisciplinary team from Germany, Canada and the UK designed and initiated a longitudinal pregnancy cohort in the United Kingdom titled Maternal mental health during the COVID-19 pandemic: Effect of the Pandemic on Pregnancy Outcomes & Childhood Health (EPPOCH).    In the second half of  2020, we recruited 3,600 pregnant individuals via self-enrollment through our website ‘www.eppoch-uk.org’. Our EPPOCH study has since collected a wealth of validated questionnaire data at multiple time points, from mothers (during pregnancy and postpartum) and their children (from birth to age 3), and we are currently distributing our 4-year childhood follow-up questionnaire. This is the first paper from the EPPOCH study.

The UK team is a collaboration between Bournemouth University and University Hospitals Dorset NHS Foundation Trust, the latter through Professor Minesh Khashu and Dr. Latha Vinayakarao based in Poole Maternity Hospital. The German team is led by Dr. Melanie Conrad, previously at Charité University Medicine Berlin, and now associated with the University of Augsburg, and includes Swarali Datye, PhD student at Charité University Medicine Berlin, whilst our Canadian collaborator, Alison MacRae-Miller, is based at the University of British Columbia, Victoria.  This EPPOCH cohort is closely linked with a sister cohort in Canada called the Pregnancy During the Pandemic (PDP) study.

 

Prof. Edwin van Teijlingen

Centre for Midwifery & Women’s Health

 

 

Reference:

  1. Datye, S., Smiljanic, M., Shetti, R.H., MacRae-Miller, A., van Teijlingen, E., Vinayakarao, L., Peters, E.M.J., Lebel, C.A., Tomfohr-Madsen, L., Giesbrecht, G., Khashu, M., Conrad, M.L. (2024) Prenatal maternal mental health and resilience in the United Kingdom during the SARS-CoV-2 Pandemic: A cross-national comparison, Frontiers in Psychiatry, (accepted).

Report on the Millennium Cohort Study (MCS) Age 17 Survey: Consultative Conference

Funding opportunities

I recently attended the Millennium Cohort Study (MCS7) Age 17 Survey: Consultative one day conference held at UCL’s Institute of Education in London. Cohort studies are extremely valuable because data is collected over time working with the same sample of people. Longitudinal studies permit to describe the natural history of the same population and can identify risk factors for example, for optimal health, educational attainment chances and/or employment opportunities. Professor Emla Fitzsimons is the Principal Investigator of MCS,m strategically invited leaders of the ‘Activities and Daily Life’, ‘Cognitive Development’, and the ‘Socio-Emotional Development’ to harness conference delegates’ view on what are the important and key issues that society should know when examining 17 year old adolescents’ lives. The leaders provided an overview of their current strategies for capturing participants’ unique style of life. Then through a series of workshops the pros and cons of these were discussed and summarised. I don’t envy their jobs! To study the individual characteristics and the associated environmental factors in such a large sample is a huge undertaking. The attendees were from very varied inter- and multi-disciplinary backgrounds working at a wide range of organisations, including government agencies. The common objective was to create a dataset that can inform many governmental policies on a variety of topics. The process of decision making over every aspects of the 7th sweep of the MCS is extremely complex. The key aspect of longitudinal studies is comparability. Although, each sweep is unique because of the cohort is ageing, there has to be a trend of using the same methodology overtime. Studies like the MCS are facing constant funding crises because they are very expensive to run. There is an ongoing revision of time taken to collect data, finding proxy to gold standard measures and considering cutting expensive data collection methods like, FMRI scans, use of accelerometers to assess physical activity patterns and conducting physical tests. Despite all of these difficulties, data from such studies are invaluable. For example, in the 7th sweep they want to omit interviewing parents about their child’s mental health. I argued to include this data at this sweep, as most adolescents in the study are still living at home and others (like family members) are the ones most likely to identify early signs of mental health problems. Early detection is vital, especially when 1 in 10 adolescents known to develop at least one serious depressive episode in the UK by the time they are 18. Check out the MCS website if you are interested. You can also access all speakers’ slides by following the link (http://www.cls.ioe.ac.uk/Conference.aspx?itemid=4285&itemTitle=MCS+Consultative+Conference&sitesectionid=28&sitesectiontitle=Events). Data from the previous 6 sweeps are available for researchers to interrogate.