Tagged / Health

What is BUCRU and what can we do for you?

What is BUCRU?

Bournemouth University Clinical Research Unit (BUCRU) is a model for supporting and conducting health related research in Dorset. It supports researchers in improving the quality, quantity and efficiency of research across the University and local National Health Service (NHS) Trusts. It does this by:

  • helping researchers with developing high quality applications for external research funding (including small grants)
  • ongoing involvement in funded research projects
  • a “pay-as-you-go” consultation service

How can BUCRU help?

BUCRU can provide help in the following areas:

  • Study design
  • Quantitative and qualitative research methods
  • Statistics, data management and data analysis
  • Patient and public involvement in research
  • Trial management
  • Ethics, governance and other regulatory issues
  • Linking University and NHS researchers

BUCRU supports Bournemouth University staff and researchers working locally in the NHS. There are no restrictions on topic area or professional background of the researcher. However we do have special interests in areas such as chronic disease and complex interventions.

How is it funded?  

BUCRU is partly funded by the National Institute for Health Research (NIHR) and incorporates the Dorset office of the NIHR Research Design Service (http://www.rds-sw.nihr.ac.uk). Further funding comes from a variety of research grants and contracts.

Contact us:

You can contact us by:

Or pop and see us on the 5th floor of Royal London House!

October is EU-tastic! The four sessions which give you all the EU funding info you need!

EU funding remains a bit of an enigma for most people. I remember how overwhelming I found it when I first began to unpick the tangle of the different funding strands, rules of participation, deadlines and conditions.Thankfully you don’t need to suffer in the same way. Horizon 2020 will be released soon (the replacement for FP7 and worth tens of billions of Euros) and I am here to guide you through it. As well as a Simple Guide to Horizon 2020 funding which I will release in early 2014 to demystify the funding schemes for you, I have arranged for four sessions to be held at BU in October to give you all the resources you need for your EU journey.

1. Health in Horizon 2020 

The European Commission National Contact Point for Health – Dr Octavio Pernas madea special trip to BU on October 7th to inform anyone interested in health research (from nursing care models to medical devices) of what to look out for under Horizon 2020 and expanding on other complementary funding programmes. The session detailed how you can make the most of the National Contact Points to help with your application. Slides from this presentation are available here: I:\R&KEO\Public\RDU\European Related\Horizon 2020\Health in H2020 Presentation.  

2. All things Horizon 2020 and 1-2-1s with UKRO

Bournemouth subscribes to information services from the fabulous UK Research Office (UKRO) and for many years they have been providing us with the latest EU information on funding calls, policy and providing advice on how to make a great application.

They will be visiting on October 9th to tell you in simple terms what Horizon 2020 is, the areas which will be funded within it and how you can make the most of UKRO by help with finding partners and gathering key bits of information. The two hour session will be followed by 1-2-1 appointments where you can get advice on your specific area of expertise and ask anything you want about EU policy making or funding. You can book your place for the information session here  and for the 1-2-1s by emailing Dianne Goodman.

 

3. All things Marie Curie

You can’t fail to have heard me banging on about how wonderful these fellowships are and how pleased I am that they will feature in Horizon 2020. These grants are absolutely the best way to kick start your EU career and you only need one non-UK partner to apply. You can either apply to have an academic come to the university from another country or you can go to another country as part of the fellowship scheme. You can have a fellowship with an academic or with an industrial partner and you can even apply for entire departments to be involved in exchanges. I’m proud of how engaged BU colleagues are with Marie Curie and the grants we already hold from this scheme.

The session is divided into two parts with both being held on October 16th. The first is a brief intro to the schemes and the second is a more detailed session on how to approach and structure your bid. You can book your place for either session here.

 

 4. The tricks of writing a winning Horizon 2020 proposal

Having already had sessions providing you with an overview of the various funding opportunities within Horizon 2020, you need to know the tricks of writing a winning bid. Writing bids for the European Commission is quite a different skill to writing for UK funders and this session on October 17th will guide you through the journey. We’ve had some fantastic feedback from this session in the past and attending will help get you on the right path to create your proposal. You can book your place for the information session here.

Desperate for uninterrupted quality time on your grant application? Come to the Residential Research Retreat!

The Research Design Service South West (RDS SW) is offering a unique opportunity to researchers in health and social care across the South West of England.

The Residential Research Retreat provides an opportunity for research teams to develop high quality research proposals suitable for submission to national peer-reviewed funding schemes. The aim of the Retreat is to provide the environment and support to promote rapid progress in developing proposals over a relatively short time period. The Retreat is open to health professionals and academic partners working within the South West. 

At the Retreat you will be supported by a range of academic experts while developing your research proposal. Away from the workplace, you will work intensively on your proposal, while learning how to maximise its chances for successfully securing a grant. You will learn how to develop your idea into a viable and first class research proposal and experience research project planning at a professional level.

A delegate from this year’s Retreat said, “This has been an extremely valuable exercise and has really helped build an understanding of what is expected from NIHR funded projects. In order to ensure that new researchers are able to make feasible, rigorous, well-designed bids for funding, this week is essential.”

The Retreat will be held at the Ammerdown Conference Centre, near Bath in Somerset from 1 June to 6 June 2014 inclusive. To win a place on the Retreat, applications should be submitted by 1pm on Friday 17th January 2014.  Applications will be reviewed competitively and places awarded to the most promising team proposals. The application and further information is available at http://www.rds-sw.nihr.ac.uk/rrr.htm.

Don’t forget, your local branch of the Research Design Service is based within the BU Clinical Research Unit (BUCRU) on the 5th floor of Royal London House. Feel free to pop in and see us or send us an email.

BU establishes Food & Drink Research Group

Early September saw the official launch of the recently formed Food & Drink Research Group (at Bournemouth University).  This cross-university research group has current membership from all schools, while formally residing under the ‘Leisure, Recreation & Tourism’ theme (See: http://blogs.bournemouth.ac.uk/research/files/2012/10/BU-Research-Themes-information-060913.pdf).  The Food & Drink Research Group focuses on a wide-range of food and drink issues ranging from consumers’ food choices to local food and drink production and distribution to healthy eating, to name.  Group members have also studied the different meanings people attach to food and eating, for example among students in Dorset and pregnant women in Nepal.

Academics associated with the Food & Drink Research Group are involved with studies focusing on consumers, the hospitality industry, food producers, wholesalers, distributors and the retailing industry. In addition, members have researched food labelling, aspects of nutrition, health promotion and education. The research group aims to act as a hub to all food and drink research activity across the University. In the spirit of Fusion, the group is focusing on student consultancy projects, PhD research, and engagement with industry.

The next meeting of the Food & Drink Research group is scheduled for November 6th at 10.30 in The Retreat at Talbot Campus.

Anybody member of staff interested in joining the group should contact Rhyannan Hurst (email: rhurst@bournemouth.ac.uk ).

CoPMRE Tenth Annual Symposium

The Centre of Postgraduate Medical Research and Education (CoPMRE) is pleased to announce its tenth annual symposium ‘Innovation in Medical Education and Research, promoting change’. The symposium is suitable for clinicians, academics, healthcare professionals and industry people (Pharma and Medical Device) with an interest in medical research and education.  

The research session will concentrate on design, assessment and implementation of novel medical devices and how to take technological innovations into practice.  The education session will explore changes in medical training from school to revalidation, now and in the future.

Date: Wednesday 16 October 2013
Venue: Bournemouth University, Executive Business Centre, 89 Holdenhurst Road, BH8 8EB
Time: 9:00am – 4:30pm

Please ensure that you register for this event in advance.

Speakers include:

Siamak Noroozi
Chair in Advanced Technology, Bournemouth University
Key performance enhancement potentials of running with blades

Ian Swain
Director of Clinical Science & Engineering, Salisbury NHS Foundation Trust
The use of electrical stimulation in Neurological Rehabilitation

Robert Middleton
Consultant Orthopaedic Surgeon Royal Bournemouth and Christchurch Hospitals NHS Foundation Trust and Visiting Fellow, Bournemouth University
Medical Device Trials – The Bournemouth Experience

Chris Pomfrett
Technical Adviser, Research Commissioning, National Institute for Health and Care Excellence (NICE)
NICE evaluation of devices and diagnostics

Mike McMillan
CEO of NHS Innovations South West (NISW)
How to make it happen and keep the day job

Chris Stephens
Associate Dean (Education & Student Experience) University of Southampton
Southampton Medical School, now and the future

Richard Marchant
Assistant Director, Regulations Policy, GMC
Regulating Medical Education and Training

Peter Hockey
Deputy Postgraduate Dean, Health Education Wessex
Higher Training and the LETB

For more details please visit our website or contact Audrey Dixon

NIHR Research Design Service Grant Applications Workshop

The Research Design Service South West (RDS SW) is running a one-day grant applications workshop on 7th November 2013 at Taunton Racecourse, Somerset.

The grant applications workshop is directed at researchers who are considering applying to peer-reviewed funding competitions for applied health or social care research, and is intended to allow them to turn good applications into excellent ones.

If you are interested in attending the workshop you will need to submit an application form and the latest draft of your research proposal by 1pm on Monday 14th October 2013.

For more information and to download an application form please go to http://www.rds-sw.nihr.ac.uk/gaw.htm.

KTP associate attends conferences to promote her research

Dr Celia Beckett, Knowledge Transfer Partnership (KTP) research associate at BU and Five Rivers Child Care Ltd attended the KTP Associates’ Conference at Brighton University on 13th June. She presented a paper on the pilot stage of her project “Improving the care of children in residential units: assessment and interventions”. The conference, which is a Brighton University initiative supported by the Centre for Collaboration and Partnership, was well attended and there were 10 paper presentations and 8 posters. Topics ranged from roller blinds to leak repair additives for coolant systems! A recurring theme at the conference was the role of the KTP in working to effect change in organisations that result in improved commercial outcomes as well as the challenges and rewards of this role.

There are c. 800 KTP associates currently working on projects throughout the UK, ensuring that there is an exchange of knowledge between Universities and private / public companies, making a real difference to all those organisations involved in KTPs. It is one of the largest graduate schemes in the UK. More information about BU’s KTPs can be found at the newly relaunched Business Pages.

Celia will also be presenting a poster at the forthcoming  Recovery-focused conference: Engagement in Life: Promoting Wellbeing and Mental Health, hosted by BU on 6th September 2013.

HSC student wins Santander Travel Grant to go to Yale

Mrs. Anita Immanuel has just been awarded a travel award from Santander to visit the Yale Cancer Centre in the USA. Anita studies the quality of lives of adults in Dorset who have survived cancer of the blood or immune system. Cancer is a devastating disease and with the advances in treatment patients are living longer, however left with debilitating side effects which can negatively affect their quality of life.

Anita’s research will identify any unmet needs in this group of patients and will give a better understanding into comprehensive survivorship care thereby maximising quality of life. This study uses a mixed methods approach in examining the quality of lives of these patients who have been treated for a haematological cancer. Data will be collected across three Dorset hospitals: The Royal Bournemouth Hospital, Poole Hospital and Dorset County Hospital.

Dr. Helen McCarthy, Consultant Haematologist at The Royal Bournemouth Hospital and Anita’s clinical supervisor, highlighted: “At Yale Cancer Centre Survivorship Clinic, Anita will be introduced to their comprehensive survivorship care programme which can help improve the quality of lives of adults treated with cancer in Dorset.

Dr. Jane Hunt, the lead supervisor and senior lecturer at Bournemouth University’s School of Health & Social Care added: “The survivorship programme at the Yale Cancer Centre Survivorship Clinic integrates a multidisciplinary approach for following up patients treated for cancer by leading experts, which differs significantly from our own. I am convinced Anita’s PhD study will benefit from collaborating with the Yale experts.

BU Prof. Edwin van Teijlingen, Anita’s third supervisor, commented “We are grateful to Santander for this funding. We know Anita’s research will significantly contribute to the underdeveloped area of research on adult haematological cancer survivors”.

For more about Santander Awards see: http://microsites.bournemouth.ac.uk/graduate-school/pgt-santander-mobility-awards/

MRC to deliver talk at BU on Healthcare funding in Horizon 2020!

I am thrilled that the MRC will be making a special trip to BU to inform us of what will be released under the Health programme in Horizon 2020 on October 7th!

The session (10- 12:30) will provide you with the opportunity to hear the latest developments in Horizon 2020 and complementary funding programmes which are most relevant for healthcare researchers, businesses and SMEs, together with a landscape of the UK based support systems and networks for SMEs and industrial engagement.

As the programme is looking for specific academia-SME collaboration we have also invited a number of SMEs to this event. A networking lunch will be followed by several 30min one-to-one sessions (from 1:30)with the MRC representative.

Places are limited – you can reserve your space and book a one-to-one by emailing Dianne Goodman before October 1st.

Insight into what will be funded under ‘Health’ in Horizon 2020

Focus of Funding – what’s different? : Europe 2020 marks out the goal to increase the number of healthy life years by 24 months by 2020 and Horizon 29020 funding will be geared towards this, focusing on health and quality of European citizens, the growth and expansion of EU industry in this area and long-term sustainability and efficiency in health and social care systems. The health focus   of Horizon 2020 will therefore be the challenge of an ageing population across Europe and in particular the health inequalities within this. Horizon 2020 will seek to transform the challenges into opportunities, focusing on active ageing, integrated care, large efficiency gains of new care modules and looks at the financial aspect that the health care market is worth €3000bn and has 85 million consumers which is ever increasing. Horizon 2020 marks a paradigm shift of ageing from a societal challenge to a major opportunity; from a burden to an asset; from acute reactive care to preventative, proactive care; and from a focus on curing diseases to improving functioning. There will be an increased focus on dissemination; not just discovering new ways to help people live longer, but getting this to ordinary EU citizens so they can begin to change their lifestyle. Involving end users will be key.

 

Types of funding: The main areas of funding are addressing major age-prevalent chronic diseases; innovation in integrated care delivery systems and innovation in independent living and social inclusion. The approach to health care will be focused on combining demand and supply sides of innovation; building on existing instruments and new ones where necessary; ownership of key stakeholder willing to invest; large-scale deployment and awareness and best-practice sharing across Europe.   It looks as though calls will be issued under 6 themes:

  • Better adherence to medical treatment
  • Prevention of falls
  • Prevention of functional decline and frailty
  • Integrated care models
  • Independent living and active ageing
  • Age-friendly buildings, cities and environments

 

How can I prepare – finding Partners: The European Innovation Partnership on Active and Healthy Ageing is the first attempt to bring together interested parties from public and private sectors to deliver innovative solutions for an ageing society. The EIP website is currently being revamped, but this is a key time to sell your research expertise to others through this virtual marketplace. Advertising your areas of knowledge and skills can help you gain partners to submit for calls under Horizon 2020.

 

FIF Networking visit to New Zealand

My Fusion journey started well before the Fusion fund came into being. Medicine 2.0 logoI’ve attended several Medicine 2.0 conferences, increasing my network of people researching in a similar area to myself along the way.  Last year this led to an invitation to visit Prof John Sullivan at the University of Otago, New Zealand. The University of Otago, founded in 1869, is New Zealand’s oldest university.

My research interests are around the role of the Internet and Social Media in supporting people living with long term conditions, and the related implications for healthcare professionals’ practice and education. Prof Sullivan researches in the area of sport concussion, including projects examining the role of the world wide web (www) in facilitating concussion awareness.

I applied to the Staff Networking and Mobility strand for support to take up this invitation, and was awarded funds for a 2 week visit to explore potential collaboration in research and education initiatives.

While I was there I was invited to give a guest lecture, where I shared some recent research I have undertaken into the ethics of using online discussion boards as research data. I was lucky enough to meet other Otago academics with an interest in this, including Dr Lynley Anderson in the Bioethics Centre, and Dr Lisa Whitehead, the Director of the Centre for Postgraduate Nursing.

I had an inspiring fortnight, mainly at the Dunedin campus. The School of Physiotherapy were kind enough to give me office space and computer access during my stay.  The University of Otago has grown over the years and has a historic core, surrounded by a collection of buildings of various ages and styles. Prof Sullivan took me on a walk around the campus and told me something of its history.

University of Otago.  Copyright C Bond
I also visited several local coffee shops, where a lot of networking meetings seem to happen. Prof David Baxter, the Dean, gave me an overview of the work of the School, and I discussed research into low back pain with Dr Ramakrishnan Mani, and use of the Internet in education with Dr Daniel Ribeiro.

I also visited the University of Otago’s Christchurch campus where Dr Whitehead is based.

The Centre for Postgraduate Nursing is located in the City Centre, and while there I took some time out to walk around the areas of the downtown area that have been opened to the public after the devastating earthquakes suffered by the city two years ago.

I’ve come back with ideas for two possible research projects that now need to be developed, and funding found.

If anyone would like to know more about my research, or to discuss the Staff Mobility and Networking fund, please email me (cbond)

 

Hello from the new Clinical Research Co-ordinator!

My name is Lisa Gale and I am the new Clinical Research Co-ordinator in Bournemouth University’s Clinical Research Unit (BUCRU). I would like to take this opportunity to introduce myself and explain a little about my role.

This is me so please say hello if you see me around!

The main focus of my role is to create a seamless link between academics at BU and clinicians in the NHS who are interested in interprofessional, high quality research to construct bids for funding, develop project plans, and conduct research. I will work with researchers across all six Schools at BU and in the health service, with a view to identifying novel collaborations and supporting the development of projects into grant applications.

The role supports BU’s key concept of fusion through creating local, regional, national and international partnerships and academic networks, undertaking world-class research, and inspiring staff to realise their full potential and enrich the world.

My passion for research developed whilst studying psychology at Cardiff University. For the past several years, I have worked in the research department of a local NHS Trust that provides mental health and community services. I have experience in co-ordinating NHS grant applications, designing, costing and delivering research projects. My background is mainly in psychology and mental health, so I am excited at the opportunity to become involved in high quality research in other areas of healthcare.

The Clinical Research Co-ordinator role is new, and over the coming weeks and months I will be visiting many departments at BU and in local NHS Trusts to discuss how the role can best support academics and clinicians alike. I look forward to meeting as many of you as possible in this time, but please feel free to contact me should you have any questions or queries, and especially if you have a novel and exciting research idea! You can contact me by email at lgale@bournemouth.ac.uk or by phone on 01202 962172.

More information about the support that BUCRU and CoPMRE can offer researchers is available through the following links:

http://microsites.bournemouth.ac.uk/bucru/  

http://www.bournemouth.ac.uk/copmre/

Presentation from Paula Kersten ‘Supporting strategies for self-management of rehabilitation in the home: a feasibility study’

You are cordially invited to a lunchtime presentation being delivered by Paula Kersten the Associate Professor of Rehabilitation at Auckland University of Technology and Visiting Professor with HSC. This is an hour long presentation entitled ‘Supporting strategies for self-management of rehabilitation in the home: a feasibility study’.  This talk would be of interest to health professionals working in health and rehabilitation.  We very much hope you will be able to attend this informative presentation.

For Paula Kersten’s Biography, please follow link below:

http://www.aut.ac.nz/profiles/paula-kersten

Thursday 16th May 2013

‘Supporting strategies for self-management of rehabilitation in the home: a feasibility study’

Presentation by Paula Kersten, Associate Professor Rehabilitation, Auckland University of Technology

12.00-1.00pm

BG11, Bournemouth House, Lansdowne Campus, BH1 3LH

 

Hosted by Clinical Research Unit

Realities of fieldwork: Sheetal Sharma, HSC PhD student on fieldwork in rural Nepal.

(c) Sheetal Sharma

Open air focus group in rural Nepal, (c) Sheetal Sharma 2013.


Roosters crowing, cows mooing, bleating goats, birds chirping, mobile phones ringing, children screaming, laughing and running around while women, breastfeeding, talk over one another excitedly in the sun as they need to leave us soon to drop the children off to school and/or head to the field to cultivate the season’s crop this spring it is wheat, last summer, rice. Women do this work as most of their husbands are away in the capital, Kathmandu or in the Arab Gulf. This is the reality of conducting focus groups in rural Nepal.

Although we, as researchers, spend considerable time to perfect the ideal ‘tool’ of the interview schedule and imagine the transcription clear and the background; a researcher must be prepared for every eventuality. Noise, din and interruptions: Today a dog nibbled on a nearby goat and a few men kept creeping to listen in why was this videshi (foreigner) recording conversations and making notes. The women shooed them away as today was a discussion on contraception; also that the discussion of the focus groups should be in ‘controlled environment’, safe, quiet; and in Nepal where women are not the main decision-maker for their reproductive health, it should mean a lieu women should be able to discuss freely these issues. In this Green Tara’s (www.greentaratrust.com) intervention area, which my PhD, supervised at HSC BU by Catherine Angell, Vanora Hundley, Edwin van Teijlingen and University of Sheffield’s Padam Simkhada, aims to evaluate both quantitatively and qualitatively, shows one the decision-making outcomes improved: increased the use of contraception in the Pharping area from 4.3% (2008) to 24.6% (2012) after 5 years of health promotion conducted by two auxiliary nurse-midwives.
40 minutes later recording (with 2 digital recorders) and once the demographic data and recording is double-checked and any last questions answered we set off walking 2 hours downhill visiting a tea-shop on the way for a cup of chai.

Edwin van Teijlingen and Emma Pitchforth, Qualitative Research: Focus group research in family planning and reproductive health care J Fam Plann Reprod Health Care 2006;32:1 30-32doi:10.1783/147118906775275299
http://jfprhc.bmj.com/content/32/1/30.citation

Assisted Living Innovation Platform (ALIP)

Promoting physical activity in older age

Invitation for proposals: The cross-Research Council Lifelong Health and Wellbeing (LLHW) programme wishes to support research into the physiological effects and behaviours associated with physical activity and sedentary behaviour in the older population.

This nine funding partner call is issued under the auspices of the cross-Research Council Lifelong Health and Wellbeing (LLHW) programme and is led by the Medical Research Council on behalf of the BBSRC, the ESRC, the EPSRC and the UK health departments: Chief Scientist Office of the Scottish Government Health Directorates, NIHR, Health and Social Care Research and Development Office, Northern Ireland and the National Institute for Social Care and Health Research, Wales.

Despite wide spread recognition of the physical and mental health benefits of physical activity at all ages, activity levels commonly decline in older age, whilst the prevalence of sedentary behaviour increases. The cross-Research Council Lifelong Health and Wellbeing (LLHW) programme wishes to support research into the  physiological effects and behaviours associated with physical activity and sedentary behaviour in the older population, which will inform the future development of effective interventions to motivate and sustain activity in this target population.  Approximately £5M is available to support research arising from this call. Applicants may apply for up to £1 million (80% fEC) for a maximum period of three years.

Key dates

   
Call open for applications in Je-S Monday 17th September 2012
Deadline for full proposals 4pm, Thursday18th October 2012
Potential triage of proposals November 2012
Commissioning Panel meeting March 2013
Decisions to applicants By end March 2013

Contact

In addition to this document, applicants should read the MRC Applicant Guidance and Frequently Asked Questions for this call.

Dr Katie Finch

MRC programme Manager for Lifelong Health and Wellbeing, E-mail: llhw@headoffice.mrc.ac.uk, Tel: 01793 416350

 The RKE Operations team can help you with your application.

BUCRU – Seminar presenting Breaking News!

 

BREAKING  NEWS…

We would like to invite you to an afternoon seminar by one of our Visiting Faculty, Professor Mike Wee, presenting some exciting new research findings to come out of a recently completed Research for Patient Benefit funded study comparing two methods of pain relief during labour (abstract and biography below).  This paper was just voted best paper of the conference at the Obstetric Anaesthetists Association Annual Conference in Liverpool and was featured recently in the Bournemouth Echo http://www.bournemouthecho.co.uk/news/9770928.Pain_relief_in_labour__study_at_Poole_hospital_makes_important_discovery/

The seminar is scheduled for Thursday 19th July 2-3pm in BG10 Bournemouth House (after the HSC end of term lunch and next door for your convenience).

We hope you can make it and look forward to seeing you then.

BUCRU

Website: http://microsites.bournemouth.ac.uk/bucru/

Administrator: +44 (0)1202 961939 / wardl@bournemouth.ac.uk

Title: The IDvIP Trial: A two-centre double blind randomised controlled trial comparing i.m. diamorphine and i.m. pethidine for labour analgesia

Research team and affiliations: MYK Wee, JP Tuckey,* P Thomas,† S Burnard,* D Jackson.

Poole Hospital NHS Foundation Trust, Poole, UK, *Royal United Hospital, Bath, UK, Bournemouth University Clinical Research Unit, Bournemouth, UK.

Abstract:

Background: Intramuscular pethidine, the commonest parenteral opioid analgesic used in obstetrics and more recently diamorphine usage has increased in the UK.  The maternal, fetal and neonatal side effects are well known for pethidine but there are no sufficiently powered large RCTs comparing pethidine with diamorphine. The aim of this trial is to address this.

Methods: After ethical approval, informed consent was obtained from 484 women randomised to receive either 7.5mg diamorphine i.m. or 150mg pethidine i.m. for labour analgesia. The sample size calculation derived from a small RCT giving 90% power (at the 5% significance level) is based upon the maternal primary outcome measure of pain relief at 60mins and the neonatal primary outcome measures of Apgar Score of <7 at 1min and neonatal resuscitation. Secondary outcome measures include verbal pain intensity at 60mins and over 3hrs post-analgesia, pain relief over first 3hrs, maternal oxygen saturation, sedation, nausea and vomiting and maternal satisfaction with analgesia. Fetal and neonatal secondary outcomes include CTG trace, meconium staining, UApH, UVpH, time of delivery to first breath, Apgar Score at 5mins, naloxone use, neonatal oxygen saturations, sedation and feeding behaviour for the first 2hrs after delivery.

Results: Reported using CONSORT guidelines. At 60mins post-administration and over a 3hr period, diamorphine is better at reducing pain scores than pethidine (p<0.001). There were no statistical differences between the two groups regarding Apgar Scores of <7 at 1min and the need for neonatal resuscitation.  The time between first dose administered and delivery is on average 82mins longer with the diamorphine group compared to pethidine (p<0.001). The vast majority of women experienced moderate to severe pain at all times. Women receiving diamorphine were more satisfied with their analgesia. There were no statistically significant differences in maternal sedation, nausea and vomiting or oxygen saturations over the 3hr period. There were no statistically significant differences in the fetal and neonatal outcomes including feeding behaviour between the two groups within 2hrs of birth but neonates in the pethidine group were more likely to be moderately or severely sedated at delivery.

Discussion: Intramuscular 7.5mg diamorphine gives significantly better analgesia than 150mg pethidine but prolongs delivery by approx. 82mins.  Women given diamorphine are more likely to be satisfied with their analgesia.  The mechanism for the prolongation of delivery time in the diamorphine group should be investigated further.

Acknowledgement: This research was funded by the NIHR Research for Patient Benefit Programme (PB-PG-0407-13170).

References

1. Tuckey JP, Prout RE, Wee MYK. Prescribing intramuscular opioids for labour analgesia in consultant-led maternity units: a survey of UK practice. International Journal of Obstetric Anesthesia 2008, 17(1):3-8.

2. Fairlie FM, Marshall L, Walker JJ et al. Intramuscular opioids for maternal pain relief for labour: a randomised controlled trial comparing pethidine with diamorphine. British  Journal of Obstetrics and Gynaecology 1999; 106(11): 1181 -1187.

Biography of speaker:

Michael Wee is a consultant anaesthetist from Poole Hospital and Royal Bournemouth Hospitals.  He has a special interest in obstetric anaesthesia and is the lead obstetric anaesthetist at Poole Hospital.  He is chair of the Research and Innovations Group at Poole Hospital and is a Board member of the Western Comprehensive Local Research Network.  He was awarded a visiting professorship at Bournemouth University in 2009.  He is a referee for several medical journals.  His research interests include patient information, safety in anaesthesia, maternal analgesia and simulation in epidural anaesthesia.  He is a co-supervisor of a PhD student at BU and chief investigator of the MObs study investigating early warning scores in obstetrics.

Active Ageing Conference

NET4SOCIETY, the network of National Contact Points for research in the field of Socio-Economic Sciences and Humanities (SSH) in FP7, is hosting an Active Ageing Conference  in Dublin on 9th-11th July 2012.

The event will be themed around the 2012 European Year for Active Ageing and Solidarity between Generations and will focus on the human and social aspects and implications of active ageing. Key note speakers include Anne-Sophie Parent, Secretary General of the AGE Platform Europe network and Lenia Samuel from the European Commission’s Directorate General for Employment, Social Affairs and Inclusion.

Thematic sessions will be based on four key topics:

  • Employment;
  • Social participation;
  • Intergenerational solidarity; and
  • Economy and innovation.

This is a great opportunity to meet potential new partners!