PhD student Orlanda Harvey featured in this month’s edition of HED Matters as Early Career Researcher (ECR) with an article on ‘ECR Spotlight: From Social Work to Studying Steroids’ . HED Matters is an online magazine about the use of legal and illegal substances to enhance the human condition published biannually by the HED network. It brings together recent advances in drug research and experiences from both drug users and practitioners. This December 2019 issue focuses on sexual human enhancers. Orlanda’s PhD research project addresses men’s experiences of recreational Anabolic Androgenic Steroid (AAS) use.
Earlier this year she also published a peer-reviewed paper form her research : “Support for people who use Anabolic Androgenic Steroids: A Systematic Scoping Review into what they want and what they access” in the Open Access journal BMC Public Health. Since there is a paucity of research on support for people using Anabolic Androgenic Steroids (AAS), this latter article synthesised the available evidence. Orlanda’s PhD I the Faculty of Health & Social Sciences is being supervised by Dr Margarete Parrish, Dr Steven Trenoweth and Prof Edwin van Teijlingen.
Congratulations to Orlanda Harvey, PhD student in the Faculty of Health & Social Sciences on her PhD publication “Support for people who use Anabolic Androgenic Steroids: A Systematic Scoping Review into what they want and what they access” in the Open Access journal BMC Public Health. Since there is a paucity of research on support for people using Anabolic Androgenic Steroids (AAS), this article searched and synthesised the available evidence in this field. Gaining an understanding of the support both accessed and wanted by recreational AAS users will be of use to professionals who provide services to intravenous substance users and also to those working in the fields of public health and social care, with the aim to increase engagement of those using AAS.
This systematic scoping review identified 23 papers and one report for review, which indicated that AAS users access a range of sources of information on: how to inject, substance effectiveness, dosages and side effects, suggesting this is the type of information users want. AAS users sought support from a range of sources including medical professionals, needle and syringe programmes, friends, dealers, and via the internet, suggesting that, different sources were used dependent on the information or support sought.
The authors argue that AAS users tended to prefer peer advice and support over that of professionals , and access information online/specialist fora, reflecting the stigma that is experienced by AAS users. These tendencies can act as barriers to accessing services provided by professionals. The paper concludes that support needs to be specific and targeted towards AAS users. Sensitivity to their perceptions of their drug-use and the associated stigma of being classified in the same sub-set as other illicit drug users is relevant to facilitating successful engagement.
Congratulations to Orlanda Harvey on the publication of her paper ‘Shades of Grey’: The Ethics of Social Work Practice in Relation to Un-prescribed Anabolic Androgenic Steroid Use. Orlanda Harvey is a PhD student in the Faculty of Health and Social Sciences with a research interest in image and performance enhancing drug (IPED) use. Her paper will be published in Practice: Social Work in Action.
This paper highlights ethical dilemmas that social workers face when assessing risk in relation to those using substances. It explores how legislation and societal factors can impact not just on people’s choices and decisions but also on their ‘vulnerability’ and access to services. Vulnerability, a contested term, is linked, in this paper, to assessment of risk. There are ethical issues that arise when assessing risk with people who use Anabolic Androgenic Steroids (AAS) from both service user and professional perspectives. These ethical issues concern a person’s right to choose whilst making potentially harmful decisions. The paper argues that using substances such as AAS in and of itself does not suffice to make a person vulnerable but this does not mean that people using AAS are not in need of support. It suggests that there may be some groups of people who are more at risk to starting AAS use and that social workers should be aware of these. It also recommends the need for further qualitative research to understand the reasons for starting use and support to help people stop using AAS.
Your hair can say a lot about you. It doesn’t just give people clues about your personality or your taste in music. It can also record evidence of how much you drink, whether you smoke or take drugs, and perhaps even how stressed you are. My colleagues and I research how hair can be used to provide more accurate testing for these attributes. And a recent court case shows how far the technology has come.
In 2008, a mother who had been struggling with alcohol abuse was asked by a UK court judging a child custody case to abstain from drinking for one year. To assess whether she managed to do this, scientists used a hair analysis that can detect long-term drug or alcohol abuse (or abstinence) over a period of many months, from just one test.
This case turned out to be a landmark moment for toxicological hair analysis. The labs analysing the mother’s hair suggested that she may have been drinking during the time she was supposed to be abstinent. The case ended up in the High Court, where the scientific principles underlying hair testing and, crucially, the way the results are reported were thoroughly debated. The judge was critical of the interpretation of the hair analysis data and disagreed with the scientists, ruling that there was no evidence to support drinking during the defined time-period.
Fast forward to 2017 and hair analysis featured in the High Court again. Yet this time the reliability of hair testing was confirmed. A lot changed in the intervening years between these cases. Technology advanced but, importantly, so did our understanding of what hair analysis data actually means.
The traditional samples for drug and alcohol testing are blood and urine. These provide evidence for cases where we require an indication of exposure to drugs and alcohol in a very recent time frame. These samples have what is referred to as a “window of detection”. This is a timeframe over which that sample can demonstrate exposure to drugs or alcohol. The window of detection for blood is often measured in hours, and urine can show evidence over a few days, possibly a few weeks.
By contrast, hair can show a retrospective history of your drug or alcohol consumption (or abstinence) over many months. This level of information makes hair testing invaluable in a wide variety of legal scenarios. If you need to screen potential employees for a safety-critical role, you can use a hair test to check they are not regular drug users. What if you’re concerned your drink was spiked at a party, but too much time has passed for any drug to still be found in your blood or urine? The drugs can remain trapped in your hair, which gives you a longer window of detection and allows scientists to find traces of the drug long after the actual crime event.
My research group is investigating factors that affect the hair concentration of certain chemicals produced when the body processes alcohol (metabolites). This sort of work is important to give confidence to the results of hair testing when presented in court. We need the utmost confidence in the data, when a court judgment may have life-changing consequences.
We recently showed that hair sprays and waxes can greatly increase the level of alcohol metabolites found in hair, giving a false positive result in an alcohol test. In one of our experiments, a volunteer who was strictly teetotal tested negative for fatty acid ethyl esters (metabolites of alcohol) in head hair untreated with hair spray, but tested positive after application of hair spray. Not just a little positive either. The volunteer tested significantly over the threshold for chronic excessive alcohol consumption after using hair spray.
This may sound alarming for a test that is used in court, but now that scientists are aware of these limitations, procedures can be put in place to mitigate against them and guidance can be updated. Ethyl glucuronide (a different alcohol metabolite) is not affected by hair sprays and waxes and so is a better target to test when someone uses cosmetic products.
Other ways of testing
Hair is not the only alternative to blood and urine testing. I’m currently investigating whether fingernails might be a better sample to test in cases where we need to prove abstinence from alcohol. It has been shown that fingernails may incorporate significantly more ethyl glucuronide (an alcohol metabolite) than hair samples. This means fingernails may be more sensitive than hair and could be better at distinguishing low levels of drinking and complete abstinence.
Toxicological hair analysis is not about catching criminals. It’s not about penalty or punishment. It’s about helping people. Results from hair testing can help support people struggling with addiction. In the future I hope we will also be using hair analysis as a diagnostic tool in healthcare.
The research I’m conducting at the moment is evaluating the potential for hair to be used as a diagnostic marker of chronic stress. Stress can lead to very serious healthcare issues. We are examining the stress hormone cortisol to see if we can identify people at risk from future healthcare issues from the concentration of this hormone in hair.
If successful, this work will take hair analysis into a new realm. I’d like to see a future where hair testing is used for a national screening programme for older adults who are most at risk from chronic stress. This could allow scientists to target interventions to lower stress at people who need them the most, which could significantly improve the health and well-being of older people in particular.
Our PhD student Orlanda Harvey is currently conducting her study on why people use Anabolic Androgenic Steroids (AAS). Since steroid use is a sensitive topic and its users are a hard-to-reach population we need as much help as we can get to get her survey distributed to as many as possible potential steroid users (aged 18 and over). We, as her PhD supervisors, would like to ask you to alert friends, family, neighbours, health care professionals working with this target group, etc. to the existence of this survey. Her questionnaire is available in paper version (from email@example.com or telephone Edwin van Teijlingen at: 01202-961564). However, the easiest and most anonymous way would be for people to complete it online using the following online link.
Thank you very much in advance!
Dr. Margarete Parrish
Dr. Steven Trenoweth
Prof. Edwin van Teijlingen
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