Congratulations to FHSS PhD student Isabell Nessel who published part of her integrated PhD thesis in the Journal for Parenteral and Enteral Nutrition last week.
The paper “Long‐Chain Polyunsaturated Fatty Acids and Lipid Peroxidation Products in Donor Human Milk in the United Kingdom: Results From the LIMIT 2-Centre Cross-Sectional Study” resulted from a collaboration between BU (Isabell Nessel, Prof Jane Murphy, Dr Simon Dyall – now at the University of Roehampton), Poole Hospital NHS Foundation Trust (Prof Minesh Khashu), and St. George’s University Hospitals NHS Foundation Trust (Dr Laura De Rooy) (1). Full text can be found here: https://onlinelibrary.wiley.com/doi/full/10.1002/jpen.1773
This paper shows for the first time that donor human milk in the UK has very low levels of essential fatty acids, which are important for brain and eye development. Furthermore, donor human milk has higher lipid degradation than preterm and term breast milk. This could have important implications for preterm infant nutrition as exclusive unfortified donor human milk feeding might not be suitable long term and may contribute to the development of major neonatal morbidities.
This study followed from a narrative review Isabell and her supervisors Prof Minesh Khashu and Dr Simon Dyall published last year, which suggested that current human milk banking practices might have detrimental effects on essential fatty acid quality and quantity in donor human milk (2).
Isabell
Reference
- Nessel, Isabell, et al. “Long‐Chain Polyunsaturated Fatty Acids and Lipid Peroxidation Products in Donor Human Milk in the United Kingdom: Results From the LIMIT 2‐Centre Cross‐Sectional Study.” Journal of Parenteral and Enteral Nutrition(2020).
- Nessel, Isabell, Minesh Khashu, and Simon C. Dyall. “The effects of storage conditions on long-chain polyunsaturated fatty acids, lipid mediators, and antioxidants in donor human milk–a review.” Prostaglandins, Leukotrienes and Essential Fatty Acids(2019).








Our
Live online event on the 8th June 2017
The amount raised will help to either
If you would like to learn more about donor milk visit the website of the
If you would like to learn more about the
using a system of 8 QTM cameras and a force plate, I measured the effect of different tasks upon the static balance in 20 young volunteers.
Special thanks go to the people who helped me at the
My supervisor Dr Simon Dyall and I were delighted to be invited to attend this event, since, together with Minesh, we are looking at the role of essential fatty acids in perinatal health. As stated above, NEC is a major health concern in the perinatal period, which potentially benefits from essential fatty acids. Furthermore, the event was a perfect opportunity to network with people working in the field of perinatal health and to get more ideas for future research.
If you would like to learn more about SIGNEC UK or attend next year’s conference, please contact Prof Minesh Khashu at
Date: 17th November
Preterm born babies are at high risk to develop a wide range of complications.
The 










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