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Capturing a yawn: initial observations – Dr Simon Thompson

Yawning presents scientists and clinicians with an intriguing phenomenon. There is continued uncertainty over its neuroanatomical origin, the neuro-chemicals involved, mechanisms involved, and its reasons of functionality. Apart from being able to visually (and aurally) observe a person yawning, it has been difficult to quantify until now.

Researchers suggest that yawning may play an important role in the protection of our immune system, by regulating hormones, and particular reflexes, when we are exposed to psychological or physical stress or fatigue (Thompson, & Zisa, 2012).

The stress hormone, cortisol may be a part of this complex response because of its involvement in the hypothalamus-pituitary-adrenal axis (Wikipedia, 2013). Cortisol, known systematically as 11-beta-11, 17, 21-trihydroxypregn-4-ene-3, 20-dione (IUPAC, 2013), is measured reliably in saliva as well as in the blood. The exact relationship between cortisol and yawning is thought to be either as a precursor to the yawn or as a result of yawning since, curiously, cortisol is found to be elevated after yawning (Thompson, & Bishop, 2012).

The yawn is produced by stretching the muscles along the jaw-line; however, the extent of stretch and volume of yawn varies between people. Measuring the level of electrical muscle activity using electromyography (EMG) at the muscle site during the yawn phase is in the region of millionths of a volt and may be sustained for several seconds.

Male and female volunteers aged between 18-53 years were exposed to conditions that provoked a yawning response in a randomised controlled trial here at Bournemouth University. For the first time, the yawn was quantified and a profile of EMG data (sine wave) was obtained.

Initial observations find that of a sample of yawners and non-yawners, induced by presentation of yawning stimuli, the people who yawned had elevated nerve activity from 50 (at rest) to 175 (after stimuli presentation and yawning) (see Photo) compared with those who did not yawn who exhibited 10 (at rest) to 80 (after stimuli presentation). Yawners generally had higher level of electrical muscular jaw activity both before and after yawning.

Further research is continuing into the “yawning envelope” (EMG wave) with the hope that, together with cortisol measurement, this new information may form part of a potential diagnostic tool to identify untoward early neurological sequelae that are indicative of neurological disease.

IUPAC – International Union of Pure and Applied Chemistry., 2013. www.iupac.org/home/about.html, Accessed 18.08.2013

Thompson, S.B.N., & Bishop, P., 2012. Born to yawn? Understanding yawning as a warning of the rise in cortisol levels: randomized trial. Interactive Journal of Medical Research 1(5);e4:1-9. Doi: 10.2196/ijmr.2241

Thompson SBN, Zisa L., 2012. Ill-health, stress, cortisol levels and yawning. In SBN Thompson (Ed.), Psychology of trauma: clinical reviews, case histories, research. Portsmouth: Blackwell-Harvard-Academic: 125-132

Wikipedia, 2013b. Hypothalamic-pituitary-adrenal axis. http://en.wikipedia.org/wiki/Hypothalamic%E2%80%93pituitary%E2%80%93adrenal_axis, Accessed: 18.08.2013

 

 

 

Inventions and Intellectual Property Law comes alive at the Festival of Design and Innovation 2013

The annual Festival of Design and Innovation (FoDI) opened on Thursday 20 June 2013.  It was an opportunity for students from the School of Design, Engineering and Computing (DEC) to exhibit their innovations and creations. “A cake icing pen, a computer game controlled by brain power and a glamping pod were just some of the ground-breaking ideas and inventions on display at this year’s FoDI.”

During the academic year, final year students from DEC are paired off with final year students from the Law Department studying Intellectual Property (IP) Law.  The law students are tasked with advising their DEC clients on the protection and exploitation of their innovative creations.  The DEC clients then incorporate the advice which they have received from the ‘lawyers’ into their final year projects.

The IP-DEC Project brings Intellectual Property law to life.  It gives an opportunity for law students to apply IP Law to real-life inventions and in turn it helps the DEC client to understand the importance of strong IP protection when preparing to protect, market and exploit their various creations.

The IP-DEC Project culminates with Awards for the Best DEC Student; Best IP Student and Best IP-DEC Group sponsored by Paul Turner, a retired Patent Attorney.

The Paul Turner Prize for the best IP-DEC Group was awarded at the opening night of the Festival.  The prize was awarded to Law Students Danielle Foster and Luke Trim and DEC Students Benjamen Armstrong, George Burge, Joseph Carter, Markko Reinberg, Nicholas Cron, Thomas Clements and Thomas Reynolds.

Paul Turner with two of the winning DEC students and law students Luke Trim and Danielle Foster.

The Paul Turner Individual Prize for the Best IP Student went to Gemma Jefferies whilst the Paul Turner Prize for the Best DEC Student was awarded to Coco Canessa.  The Individual Prize winners will officially receive their awards at the Graduation Ceremony in November 2013.

The opportunity to apply Intellectual Property Law to real-life scenarios and to real-life innovations together with helping the DEC clients to grasp the importance of IP law, makes this project truly unique.

The IP-DEC Project is co-ordinated by Dr. Dinusha Mendis (Law); Dr. Tania Humphries (DEC); and Dr. Reza Sahandi (DEC).

 

Challenges of Leadership

Leadership is a word often bandied about with many people claiming, assuming or being allocated ‘leadership’ roles, but what does this actually mean when trying to bring about societal improvements? Last week as part of an NHS South of England project BU and Plymouth University hosted a 2 day workshop for strategic leaders in the NHS, Local Authorities and the voluntary sector responsible for strategic leadership in the world of dementia in Devon, Dorset and Somerset. The aim of this project is to promote improvements in the provision of dementia care at a time of fiscal challenge. Working across organisational and disciplinary boundaries, learning from others and acting rather than just talking about the policy directives and vision that contextualises dementia is key. We had several high profile speakers at the workshop, including the Chief Executive of the Alzheimer Society, Jeremy Hughes; the Clinical Lead for dementia for NHS England, Prof Alistair Burns; the immediate Past President of the Association of Directors of Adult Social Services (ADASS), Sarah Pickup; Angela Rippon a high profile ambassador for the Alzheimer Society as well as BU’s own director of the NCPQSW. Prof Keith Brown who does a lot of leadership training across the country. We also had a person living with dementia reminding us of why it is of utmost importance to ensure that people with dementia can live well with their dementia and really what the workshop was all about. Key messages I took from the 2 days that are perhaps transferable to anyone with a leadership role are first that it sometimes just important to get on and do what you need to do because it is the ‘right thing to do’ and this may be at odds with procedures, other colleagues perceptions and priorities but still worth doing! Good leaders sometimes need to buck the trend and with convention, and there were lots of dementia specific examples about how people have been innovative in challenging times. Another key leadership message related to working together and learning from others rather than reinventing the wheel. None of these are new messages but do highlight the ongoing challenges those with key strategic roles face as they work to address key societal concerns.

Festival of Learning – Testament to a Successful Morning (Dr Simon Thompson, DEC Psychology Research Centre)

‘Testamentary Capacity in Dementia’ (03 June 2013 10:00h – 13:00h) – Presentation followed by in-depth plenary session about the complexities of leaving an estate to beneficiaries following a diagnosis of dementia.

‘Dementia’ is an umbrella term used to describe many types of deteriorating diseases – the most common ones are Alzhiemer’s disease, Vascular dementia, and Lewy body dementia.

Many married couples own property as ‘joint tenants’. Upon death, ownership automatically passes to the survivor. If property is owned as ‘tenants in common’, one half of the estate belonging to the deceased is dealt with by their Will. Problems arise when there is no Will, when others make a claim, or when another Will is executed.

‘Testamentary capacity’ is a person’s legal and mental ability to make a
valid Will. There are three premises: Presumption of capacity; Requirements; Proof of testamentary capacity.

It is proposed that the law should allow testators alternative means of satisfying the testamentary capacity standard such as an option to validate a testator’s capacity during their lifetime through forensic assessment measuring cognitive elements of testamentary capacity.

It does not remove the difficulty of knowing the status of person at a specific time line. However, it goes some way to describing a person during their lifetime in terms of mental ability and capacity.

Thompson, SBN (2006). Dementia and memory: a handbook for students and professionals. Aldershot: Ashgate.

Thompson, SBN (2012). Dementia. In SBN Thompson (Ed), Psychology of trauma: clinical reviews, case histories, research (pp169-202). Portsmouth: Blackwell-Harvard-Academic.

Does Guinness taste different in Dublin?

In August 2012 a call was put out through the midwifery networks by the Preterm Birth Clinical Study Group (CSG) who were seeking to recruit new members. The Preterm Birth CSG aims to identify important research questions around preterm birth and to work with the originators of supported studies around preterm birth, and to improve clinical outcomes following preterm birth by prevention or intervention.

This group, one of 11 CSGs, is a Royal College of Obstetrics and Gynaecology (RCOG) specialist group supported by British Maternal and Fetal Medicine Society (BMFMS), British Association of Perinatal Medicine (BAPM) and by Action Medical Research. Applications were welcomed from obstetricians, neonatologists and midwives who were interested in preventing preterm birth or in improving outcomes. I (Luisa Cescutti-Butler) was successful in my application and attended my first meeting on the 23rd April 2013 in Dublin.

Most of us were new to the group and following introductions we set to business. An urgent consideration was the representation of lay members. There were a number of suggestions put forward as to how lay members could be approached and groups such as MumsNet, Bliss and Bounty were to be approached for their views on research priorities within preterm birth. The group also felt that establishing a focus group of women who had experienced a preterm birth would be valuable and I offered to facilitate this.

A number of research projects were discussed and whilst many of these studies were focused on RCT’s and not within my comfort zone, I was able to provide input into some where a qualitative approach would work. Many of the professors around the table were comfortable with scientific methodologies, but were open to the possibilities of where proposed projects might benefit from a qualitative perspective, i.e. inviting women to speak about their experiences of possible interventions to prevent preterm birth.

Following the Preterm Birth Clinical Study Group meeting on the 23rd April 2013, I was fortunate to attend on the following two days a conference arranged by the British Maternal and Fetal Medicine Society (BMFMS) of which I am a member. The programme, which consisted of high quality clinical and basic science key lectures and presentations were fascinating for me as a midwife, although I did feel at various points throughout the two days that if it were left to ‘science’, women would never have an opportunity to have a normal pregnancy and birth. It appeared that every step of the childbirth continuum could be researched, with outcomes managed in some way because of ‘evidence,’ which for some women who experience life threatening conditions such as pre-eclampsia is of vital importance. In the event, I was able to gain information that would benefit BU undergraduate midwifery students. At the end of the conference I was in awe of all the high quality research being undertaken in the UK to prevent preterm birth and obstetric conditions such as pre-eclampsia, but also a little sad. Sad at the prospect that if midwives don’t continue to protect normality for women, it might fall forever within the realms of ‘medicine’ and who knows where pregnant women will end up? And finally in conclusion, I never did get to taste a Guinness in one of the many traditional Irish Pubs scattered around the city, so couldn’t say whether it tasted better in Dublin or not!

BU and University of Ljubljana working together to enhance midwifery practice

Slovenia, once part of communist Yugoslavia, is now an independent country which borders Italy, Croatia, Austria and Hungary. It is a modern and young economy with a strong infrastructure.  Midwifery has been practised in the region for hundreds of years; however a decision to suspend midwifery training in the 1980s resulted in a severe shortage of midwives.  In 1996 midwifery education was reinstated, but this time within higher education. In 2002 the first midwives were able to qualify with a degree from the University of Ljubljana, which offers the only undergraduate midwifery programme in Slovenia.

The role of the midwife in Slovenia is mainly concentrated within the area of intrapartum care; a consequence of the midwifery shortage that saw midwives drawn from other areas to cover labour and birth. Very little antenatal and postnatal care is offered by midwives. These aspects of care are typically provided by gynaecologists, obstetricians, paediatricians and community nurses. Thus there have been calls for midwives to increase their role within public health and to develop primary care services. One aspect of care that could develop midwifery practice is examination of the newborn.

A scoping visit funded by ERASMUS (British Council) and EUNF (Bournemouth University) was undertaken by Luisa Cescutti-Butler (Senior Lecturer) and Professor Vanora Hundley at the behest of the Head of Midwifery Dr. Ana Polona Misvek at the University of Ljubljana. The visit explored whether midwives, paediatricians, neonatologists and midwifery lecturers would be receptive to a course that would teach Slovenian midwives to examine normal healthy term babies. This examination is currently only undertaken by paediatricians.

A round table discussion was arranged with key professionals from the medical and midwifery community. The discussion was at times fairly animated; for example there was strong opposition from the neonatologist who believed that midwives were not ready to take on this role. In contrast, there was encouraging agreement from Professor Dr. Ciril Kržišnik (Senior Paediatrician and Head of the Paediatric Association) who was present, and Anita Prelec (Head of the Slovenian Nursing/Midwifery Association).

A positive outcome was the desire from all professionals to strengthen the midwife’s role within the initial examination of the newborn and it is this aspect of care and knowledge that offers further opportunities for future collaboration and training.

For further details about this study contact: Luisa Cescuttti Butler, Senior Lecturer, Lansdowne Campus.

European Science Foundation and Global Changes in the Marine Environment

I was very proud to have been invited by the Institute of Marine Sciences – National Research Council (ISMAR-CNR) in Venice who developed on the European Science Foundation Platform, the Exploratory Workshop:  Marine woodborers: New Frontiers for European Waters. And I have to say that that was one of the most exciting research opportunities I have taken part of in the recent past.

The European Science Foundation (ESF) was established in 1974 to provide a common platform for its Member Organisations to advance European research collaboration and explore new directions for research. Currently it is an independent organisation, owned by 67 Member Organisations, which are research funding organisations, research performing organisations and academies from 29 countries.

The focus of the Exploratory Workshops scheme is on workshops aiming to explore an emerging and/or innovative field of research or research infrastructure, also of interdisciplinary character. Workshops are expected to open up new directions in research or new domains. It is expected that a workshop shall conclude with plans for follow-up research activities and/or collaborative actions or other specific outputs at international level.

The organisers, namely Davide Tagliapietra, Erica Keppel and Marco Sigovini – all from the ISMAR-CNR- did an amazing job in organising this much needed research group and by planning an excellent working programme.

The topic, centred on Marine woodborers is of utmost important as these organisms are a threat to maritime structure and archaeological heritage. Recently, an increase in attack and a northward spread has been reported. Despite the ecological, economical and cultural importance, research on this subject is carried out by few scientists scattered across Europe. An interdisciplinary approach is needed to reach a synthesis of knowledge and a deeper understanding of the causal factors. The main outcome of the workshop is the establishment of a research network aiming to coordinate scientists with an European perspective and a global view. Through the establishment of such a network, new theoretical and technical developments could be achieved.

The agenda of the workshop was to focus on:

1) bringing together experts in complementary fields that have hitherto not collaborated as a group;

2) identifying additional research competences that are not covered within the group of participants;

3) identifying, exchanging and sharing research interests for future joint leading research projects and developing an application strategies;

4) the establishment of an international network on marine woodborers.

Despite the subject ([wood-]‘boring’ organisms), there wasn’t a single dull moment. It was very exciting to spent a considerable amount of time with international peers coming from as far as Colombia and discussing the problems surrounding these particular organisms.

All sessions were extremely interesting and productive and I totally enjoyed chairing one of them in the Knowledge Café, with my hat of maritime archaeologist whose research interest based also based on marine organisms and global changes, but I am also one of few who combines degradation and protection of the cultural heritage and marine science. The Knowledge Café focussed on Systematics and biogeography, Marine woodborer-microorganism interactions, Protection of shipwrecks and maritime structures. Each group discussed weaknesses: Problems, constrains and bottlenecks, Strengths: Opportunities, synergies, and Perspectives: Solutions, actions and recommendations.

19 international peers attended, which was by invitation only, this amazing opportunity, some of which were old friends and some of which have become reference points for my current and future research on wood borers.

All with the amazing architectural beauties of a tiny Venetian island just in front of one of the world most famous squares: San Marco square!

Paola Palma