Tagged / Health

Keeping it clean… BU leads new insights into blood filtration

Whether its in you, a blue whale or a tiny insect, circulating fluids bathe and nourish organs, tissues and cells. To avoid compromising organ function, these ‘bloods’ are filtered and kept free of unwanted molecules. Studying these clearance mechanisms informs us about normal physiology, as well as disease across a vast array of organisms, from flies to humans.

In a new paper led by BU, it has been established that a mechanism common to flies and humans involving a protein called Amnionless, relies on a cell’s calcium level being controlled by genes known as Stim and Orai. Using powerful fruit fly genetics and dynamic cellular imaging techniques, the researchers found that as calcium levels change, Amnionless is turned-over at the cell surface where is helps to remove unwanted molecules. This new information is important because of its relevance to the human kidney’s role in blood filtration. Additionally, research is showing that the mechanism can be targeted by environmental toxins and this may explain why some insect species are struggling in the wild.

It is sobering to think that aspects of human cardiovascular disease and the ‘insect apocalypse’ may actually have common origins. Understanding these biological systems therefore has a dual purpose by informing medical, biomedical and ecological research fields.

(The image shows insect filtration cells in blue, adjacent to the heart, coloured magenta).

NIHR’s ‘Your Path in Research’ campaign

The National Institute for Health and Care Research’s (NIHR) Your Path In Research campaign kicks off on Monday 31 October 2022 with a special 2 week focus on research careers in public health and social care.

The campaign will highlight how public health and social care staff can make research part of their career.

They will showcase inspiring case studies from those working in the field and give people the opportunity to chat and connect with researchers online via their Link and Learn matchmaking service.

You can find more information on this here,

Free online course – Improving Healthcare Through Clinical Research

Interested in clinical research and what’s involved? Are you contemplating a career in healthcare or the life sciences, or, do you want to find out more about the role of clinical research in improving healthcare?

If you’ve answered yes to any of the above questions, then why not sign up to FutureLearn’s Improving Healthcare Through Clinical Research course?

The course has been developed by the University of Leeds and is be available now, via this link.

It is completely free and all online, lasting 4 weeks.

This course has been certified by the CPD Certification Service as conforming to continuing professional development principles. By completing the course you will have achieved 16 hours of CPD time.

Remember – support is on offer at BU if you are thinking of introducing your research ideas into the NHS – email the  Clinical Research mailbox, and take a look at the Clinical Governance website.

New BU midwifery paper published this week

Congratulations to Prof. Vanora Hundley in the Centre for Midwifery, Maternal &Perinatal Health (CMMPH) who published the paper ‘Effective communication: core to promoting respectful maternity care for disabled women’ in the international journal Midwifery. This paper is co-authored with BU Visiting Faculty Jillian Ireland who is Professional Midwifery Advocate at Poole Maternity Hospital, University Hospital Dorset (UHD), and two former BU staff members: Dr. Bethan Collins & Dr. Jenny Hall.

Congratulations,

Prof. Edwin van Teijlingen

Reference: 

Collins, C., Hall, J., Hundley, V., Ireland, J. (2022) Effective communication: core to promoting respectful maternity care for disabled women’, Midwifery. https://doi.org/10.1016/j.midw.2022.103525

 

 

Congratulations to Dr. Tsofliou & Prof. Appleton on latest interdisciplinary paper

Congratulations to BU’s interdisciplinary nutrition-behavioural sciences team that published the recent review “Barriers and Facilitators Associated with the Adoption of and Adherence to a Mediterranean Style Diet in Adults: A Systematic Review of Published Observational and Qualitative Studies” [1] in the journal NutrientsThe academics are based in two different faculties, namely the Faculty of Health & Social Sciences and the Faculty of Science & Technology, represented by Dr. Fotini Tsofliou and Prof Katherine Appleton respectively.  Two BU students (recently graduated) are also two co-authors: Dimitrios Vlachos (who completed the MRes) and Christina Hughes (MSc Nutrition & Behaviour).

This review which is Open Access includes all studies investigating barriers or facilitators to adopting or adhering to a Mediterranean style diet in adults aged 18 years old and over.  The paper identified  financial, cognitive, socio-cultural, motivational, lifestyle, accessibility & availability, sensory and hedonic and demographic factors. Similar barriers and facilitators are often reported in relation to healthy eating or the consumption of specific healthy foods, with a few exceptions. These exceptions detailed concerns with specific components of the MedDiet; considerations due to culture and traditions, and concerns over a cooler climate. Suggestions for overcoming these barriers and facilitators specific to adoption and adherence to the Mediterranean diet are offered. 

Well done!  nutrients-logo

Prof. Edwin van Teijlingen

CMMPH

 

Reference:

  1. Tsofliou F, Vlachos D, Hughes C, Appleton KM. Barriers and Facilitators Associated with the Adoption of and Adherence to a Mediterranean Style Diet in Adults: A Systematic Review of Published Observational and Qualitative Studies. Nutrients. 2022; 14(20):4314. https://doi.org/10.3390/nu14204314

Free Upcoming Seminars

See below for two opportunities to attend free seminars.

Selling to the NHS

Thursday 3rd November – 13:00-14:30
A Healthcare Innovator’s roadmap. This course will help you address key market access challenges in healthcare.

This 90 minute session is suitable for anyone who is involved in developing new healthcare technologies and products, be it as an entrepreneur, clinician, academic or investor. It will help you to understand key market issues in healthcare markets and how to overcome them, understanding your (NHS) customer and the value of evidence and how to use it to drive adoption.

BOOK YOUR FREE PLACE HERE

Grant Funding Opportunities for MedTech Innovators

Thursday 10th November – 12:30-13:30
This free 60 minute session is suitable for anyone from the NHS, academia or industry looking to learn more about how to prepare robust funding applications to support the development of new medical technologies.

BOOK YOUR FREE PLACE HERE

Erasmus+ students from Nepal arrived at BU

Last Thursday the seven Erasmus+ exchange students arrived in Bournemouth from Nepal.  The exchange is between Bournemouth University (BU) and Manmohan Memorial Institute of Health Sciences (MMIHS) in Kathmandu, Nepal.  On Friday, their first full day a BU the Nepalese M.Sc. students received a Global Engagement Welcome from Cathryn Street, followed by an International Orientation by Caroline Earth from the Transitions Team.  The students were welcomed to the Faculty of Health & Social Sciences by Dr. Angela Turner-Wilson who is Deputy Head of the Department of Medical Sciences & Public Health as well as the faculty’s Interim Associate Dean of Global Engagement.  The two main contacts for the students at BU will be Dr. Pramod Regmi and Prof. Edwin van Teijlingen.  This student exchange follows the visit of BU staff (Profs. Vanora Hundley & Edwin van Teijlingen) to Kathmandu and MMIHS staff visiting BU in return this summer.

 

Prof. Edwin van Teijlingen

Centre for Midwifery, Maternal & Perinatal Health (CMMPH)

New BU PhD education paper

This week the editor of the journal Journal of Education & Research informed us that our paper ‘Reflections on variations in PhD viva regulations: “And the options are….”’ has been accepted for publication [1].  This paper grew out of a discussion between the six authors about the apparent differences between the outcomes of the PhD viva at different universities.  We have all acted as internal or external examiners for a PhD viva and had noted inconsistencies between universities, either in the regulations or in the interpretation of their PhD regulations.  The authors are based at three different universities, on two different continents and, between them, have examined PhD theses submitted to universities based in at least ten different countries.  Three authors are based in BU’s Faculty of Health & Social Sciences (Prof. Vanora Hundley, Dr. Pramod Regmi & Prof. Edwin van Teijlingen), two authors are based in the School of Human & Health Sciences at the University of Huddersfield (Prof. Padam Simkhada & Dr. Bibha Simkhada and both are Visiting Faculty at BU), and one author is based in the Institute for Global Health in the School of Public Health & Health Sciences at the University of Massachusetts Amherst, USA (Prof. Krishna C. Poudel).

This paper outlines the range of outcomes of a PhD examination.  It also includes four short case studies, each reflecting on a particular aspect /differences we experienced as examinees or as examiners. The authors aim to alert PhD candidates and examiners to study the examination rules set by the awarding university, as the details of the PhD examination outcome, and hence the options available to both examiners and the students, may differ more than one might expect.  This is the latest CMMPH education publication around aspects of the PhD [2-5].

 

Prof. Edwin van Teijlingen

Centre for Midwifery, Maternal & Perinatal Health (CMMPH)

 

References:

  1. van Teijlingen, E., Simkhada, B., Regmi, P., Simkhada, P., Hundley, V., Poudel, K.C. (2022) Reflections on variations in PhD viva regulations: “And the options are….”, Journal of Education and Research (accepted).
  2. Way, S, Hundley, V., van Teijlingen, E, Walton, G., Westwood, G. (2016) Dr Know. Midwives 19: 66-7.
  3. Wasti, S.P. Regmi, P.R., Simkhada, P., van Teijlingen, E., Hundley, V. (2022) Writing a PhD Proposal, In: Wasti, S.P., van Teijlingen, E., Simkhada, P.P., Hundely, V. & Shreeh, K. (Eds.) Academic Writing and Publishing in Health & Social Sciences, Kathmandu, Nepal: Himal Books: 176-183.
  4. Hundley, V., Simkhada, P., van Teijlingen, E. (2022) Converting your Master’s or Doctoral Thesis into an Academic Paper for Publication, In: Wasti, S.P., et al. (Eds.) Academic Writing and Publishing in Health & Social Sciences, Kathmandu, Nepal: Himal Books: 184-189.
  5. Regmi, P., Poobalan, A., Simkhada, P., van Teijlingen, E. (2021) PhD supervision in Public Health, Health Prospect: Journal of Public Health 20(1):1-4. https://www.nepjol.info/index.php/HPROSPECT/article/view/32735/28111

Could you help the Health Research Authority improve the research ethics review?

Remember – support is on offer at BU if you are thinking of introducing your research ideas into the NHS or social care – email the Clinical Research mailbox, and take a look at the Clinical Governance section of the website.

Reminder – Spotlight on Wellcome Trust TODAY

The RDS Funding Development Briefings occur weekly, on a Wednesday at 12 noon.

Each session covers the latest major funding opportunities, followed by a brief Q&A session. Some sessions also include a spotlight on a particular funding opportunity of strategic importance to BU.

Today, Wednesday 22nd June, there will be a spotlight on the Wellcome Trust.

We will cover:

  • Overview
  • Their Discovery Research schemes
  • Q & A

For those unable to attend, the session will be recorded and shared on Brightspace here.

Please join the briefing by clicking the link below.

Click here to join the meeting